Results 101 to 110 of about 1,428,643 (254)
Quantitative nanohistological investigation of scleroderma: An atomic force microscopy-based approach to disease characterization [PDF]
, 2017 Scleroderma (or systemic sclerosis, SSc) is a disease caused by excess crosslinking of collagen. The skin stiffens and becomes painful, while internally, organ function can be compromised by the less elastic collagen.
Aguayo, S +7 more
core +1 more source
Revolutionizing Autoimmune Research: The Role of Caveolin‐1
Immunity, Inflammation and Disease, Volume 13, Issue 8, August 2025.ABSTRACT Introduction Caveolins (Cav) include Cav‐1, Cav‐2, and Cav‐3, with Cav‐1 being the most studied due to its prominent role as a major component of plasma membrane caveolae. Cav‐1 is involved in a wide range of cellular functions and plays a key role in regulating signaling pathways related to immune responses and inflammation.
Yanan Gao +8 more
wiley +1 more source
Selective deletion of PPARβ/δ in fibroblasts causes dermal fibrosis by attenuated LRG1 expression. [PDF]
, 2018 Connective tissue diseases of the skin are characterized by excessive collagen deposition in the skin and internal organs. Fibroblasts play a pivotal role in the clinical presentation of these conditions.
Chan, JSK +17 more
core +3 more sources
Progressive Hemifacial Atrophy with Morphea of Cheek
Journal of Indian Academy of Oral Medicine and Radiology, 2006 Scleroderma is a rare collagen disorder in which fibrosis of skin, subcutaneous tissues and muscles can occur with occasional involvement of bones. Localized scleroderma is a benign condition but can cause significant deformity when it affects the face ...
Ajit Auluck, Keerthilatha M Pai
doaj
Лечащий ВрачBackground. Localized scleroderma may be associated with a malignant process occurring in the body. The onset of scleroderma does not always coincide with the onset of clinical manifestations of oncology.
P. O. Kazakova
doaj +1 more source
The role of Borrelia burgdorferi infection in scleroderma
Rheumatology, 2014 Borrelia burgdorferi , a Gram-negative, spiral-shaped bacterium transmitted to humans via tick bites, is the etiologic agent of borreliosis (Lyme disease) with diverse clinical manifestations. There are several types of pathological lesions in the course
Żaneta Smoleńska +3 more
doaj +1 more source
Mangiferin Against Respiratory Diseases: Pharmacological Targets and Prospects
Pharmacology Research &Perspectives, Volume 13, Issue 4, August 2025.ABSTRACT Respiratory diseases are associated with high mortality worldwide. Respiratory infections can lead to the emergence of chronic respiratory diseases. Scientists are constantly striving to identify new therapies with reduced side effects.
Kazi Ahsan Ahmed +10 more
wiley +1 more source
Localized scleroderma is an autoimmune disorder [PDF]
Rheumatology, 2005 There have been many studies suggesting that localized scleroderma has a strong autoimmune background, although the lesions are usually limited to the skin and subcutaneous tissue. Here we summarize previous data on the autoimmunity of localized scleroderma, mostly published in the last two decades, because there has not been a review paper summarizing
Kazuhiko Takehara, Shinichi Sato
openaire +2 more sources
Protein kinase Cδ and c-Abl kinase are required for transforming growth factor β induction of endothelial-mesenchymal transition in vitro. [PDF]
, 2011 OBJECTIVE: The origin of the mesenchymal cells responsible for the intimal fibrosis in systemic sclerosis (SSc) has not been fully identified. The present study was undertaken to investigate whether subendothelial mesenchymal cells may emerge through ...
Jimenez, Sergio A., Li, zhaodong
core +2 more sources
Localized scleroderma in a newborn (case report) [PDF]
РМЖ. Мать и дитя, 2022 N.I. Akhmina1, P.S. Utkin2, M.P. Shalatonin3, Zh.L. Chabaidze1, A.A. Dement’ev1, A.L. Zaplatnikov1 1Russian Medical Academy of Continuous Professional Education, Moscow, Russian Federation 2Children’s Infectious Clinical Hospital
N.I. Akhmina +5 more
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