Results 101 to 110 of about 1,480,350 (249)

The lens as a model for fibrotic disease [PDF]

open access: yes, 2011
Fibrosis affects multiple organs and is associated with hyperproliferation, cell transdifferentiation, matrix modification and contraction. It is therefore essential to discover the key drivers of fibrotic events, which in turn will facilitate the ...
Dawes, LJ, Eldred, JA, Wormstone, IM
core   +2 more sources

Scleroderma-Like Lupus Panniculitis: A Case Report and Literature Review

open access: yesClinical, Cosmetic and Investigational Dermatology, 2023
Prinpat Pinyowiwat, Suthinee Rutnin, Kumutnart Chanprapaph Division of Dermatology, Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, ThailandCorrespondence: Kumutnart Chanprapaph, Division of Dermatology ...
Pinyowiwat P, Rutnin S, Chanprapaph K
doaj  

Biological effects of a new ultraviolet A1 prototype based on light‐emitting diodes on the treatment of localized scleroderma

open access: yesExperimental Dermatology, 2020
Ultraviolet A1 (UVA1) phototherapy (spectral range 340‐400 nm) is a well‐established treatment option for various skin diseases such as localized scleroderma. Recent improvements of conventional UVA1 light sources (metal‐halide or fluorescent lamps) have
S. Arndt   +5 more
semanticscholar   +1 more source

Hyaluronic Acid Filler Injection for Localized Scleroderma – Case Report and Review of Literature on Filler Injections for Localized Scleroderma

open access: yesClinical, Cosmetic and Investigational Dermatology, 2022
Jaishree Sharad Skinfiniti Aesthetic Skin and Laser Clinic, Mumbai, Maharashtra, IndiaCorrespondence: Jaishree Sharad, Skinfiniti Aesthetic Skin and Laser Clinic, 601, Prabhat Chambers, Khar West, S.V.Road, Mumbai, Maharashtra, 400052, India, Tel ...
Sharad J
doaj  

How I explore ... the skin functional involvement in scleroderma [PDF]

open access: yes, 2013
peer reviewedScleroderma refers to distinct clinical presentations sharing in common a sclerotic process most often clinically obvious on the skin. The involvement possibly affects the skin alone in morphea or in combination with internal lesions in ...
Andre, B.   +6 more
core  

Clinical pattern of systemic sclerosis in Central Ukraine. Association between clinical manifestations of systemic sclerosis and hypertension [PDF]

open access: yes, 2018
Objectives: Systemic sclerosis (SSc) is a rare disease of connective tissue, manifestations of which may vary in different geographical areas. We aimed to describe the clinical portrait of patients with SSc in Dnipropetrovsk region and to investigate how
Kuryata, O., Lysunets, T., Semenov, V.
core   +1 more source

Mapping the Tissue‐of‐Origins of Mesenchymal Stromal Cells in Injury Repair

open access: yesAdvanced Science, Volume 13, Issue 3, 14 January 2026.
This study maps mesenchymal stromal cells (MSCs) across multiple tissues, revealing that bone marrow–derived MSCs mobilize monocytes via CCL2 to promote systemic inflammation but do not migrate to distant organs to form fibrotic or tumor stroma. Instead, local MSCs dominate tissue remodeling, suggesting a “two‐hit” model linking systemic inflammation ...
Xinyu Thomas Tang   +4 more
wiley   +1 more source

Systemic sclerosis: current views of its pathogenesis. [PDF]

open access: yes, 2003
Systemic sclerosis (SSc) is an autoimmune disorder of unknown etiology characterized by severe and often progressive cutaneous and visceral fibrosis, pronounced alterations in the microvasculature, and numerous cellular and humoral immune abnormalities ...
Derk, Chris T., Jimenez, Sergio A.
core   +2 more sources

Stress‐Induced Activation of Prolactin‐NR4A1‐Midkine Axis Exacerbates Skin Inflammation

open access: yesAdvanced Science, Volume 13, Issue 5, 27 January 2026.
Chronic psychological stress activates prolactin signaling to reprogram dermal fibroblasts into APCDD1+ inflammatory effectors via NR4A1, driving midkine secretion. This paracrine hub amplifies keratinocyte proliferation and immune recruitment, thus exacerbating skin inflammation.
Zhiguo Li   +18 more
wiley   +1 more source

Pansclerotic Morphea with Features of Eosinophilic Fasciitis: Distinct Entities or Part of a Continuum? [PDF]

open access: yes, 2014
Scleroderma is a highly complex disorder in its clinical manifestations and pathogenesis. It has a wide range of clinical manifestations due to varying degrees of vasculopathy, autoimmunity, altered endothelium function, and abnormal fibrosis.
Canty, Kristi   +2 more
core   +1 more source

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