Results 91 to 100 of about 471,570 (210)

Localized severe scleroderma: a retrospective study of 26 pediatric patients

, 2010
Juvenile localized scleroderma includes different conditions characterized by skin hardening with increased collagen deposition. Although juvenile localized scleroderma is considered a relatively benign disease, lesions may extend through the dermis ...
M. Beltramelli, Adina Frasin, A. Frasin, C.M. Gelmetti, Fabrizia Corona, P. Vercellesi, Matilde Beltramelli, Paolo Vercellesi, F. Corona, Carlo Gelmetti   +9 more
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Successful treatment of localized scleroderma using brodalumab: A case report

SAGE Open Medical Case Reports
We report the first documented use of brodalumab, an IL-17 receptor antagonist, for treating severe linear localized scleroderma refractory to conventional therapies, including methotrexate, mycophenolate mofetil and corticosteroids.
Alexandra Carla Bobica, Catherine Zhu, Catherine Silotch, Hessah BinJadeed, Elena Netchiporouk   +4 more
doaj   +1 more source

Elevated Serum BAFF Levels in Patients with Localized Scleroderma in contrast to other organ-specific autoimmune diseases [PDF]

, 2007
Serum levels of B-cell activating factor belonging to the tumor necrosis factor family (BAFF), a potent B-cell survival factor, are elevated in patients with systemic autoimmune diseases, such as systemic lupus erythematosus (SLE), rheumatoid arthritis ...
45413, Takehara, Kazuhiko, 45412, 20168, 45414, 45411, 45410, 50142253, Hasegawa, Minoru, Matsushita, Yukiyo, 20219, Sato, Shinichi, Horikawa, Mayuka, 60432126, Ogawa, Fumihide, 143, 50283130, 304, Wayaku, Takamasa, Matsushita, Takashi, Echigo, Takeshi, 20215792   +21 more
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Localized scleroderma: case report and literature review. [PDF]

Background. Localized scleroderma is a rare chronic autoimmune inflammatory disorder, belonging to the spectrum of sclerosing skin diseases, affecting patients of any age, more frequently Caucasian females.
Pargaliauskaitė, Julija,
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Experience with Lipofilling in Children with Localized Scleroderma: Case Study

Вопросы современной педиатрии
Background. Localized scleroderma (LS) is an inflammatory sclerosing disease of unknown etiology. It is characterized by progressive lesion of connective tissue leading to sclerosis and/or atrophy of the skin and underlying tissues.
Alina R. Misbakhova, Nataliya E. Manturova, Larisa S. Kruglova, Nikolay N. Murashkin, Sofiya R. Mayransaeva   +4 more
doaj   +1 more source

Psychometric properties of the Children’s Dermatology Life Quality Index in pediatric localized scleroderma

, 2018
Introduction: The Children’s Dermatology Life Quality Index has been used to measure quality of life in studies of pediatric localized scleroderma, which suggested only modest effects on quality of life.
Christina K Zigler, Galen E Switzer, Kathryn S Torok, Kaveh Ardalan, Nicole M Hershey   +4 more
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Janus kinase inhibitors in localized scleroderma: a systematic literature review

BACKGROUND/AIM: Reports on the use of Janus kinase (JAK) inhibitors in the treatment of localized scleroderma are increasing in the literature. In this review, we examined the published studies regarding the use of JAK inhibitors in patients with ...
AKDOĞAN, Ali, ŞENER, Yusuf Ziya, BATU, Ezgi Deniz, SARI, Alper, ŞENER, Seher   +4 more
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Case of localized scleroderma associated with osteomyelitis. [PDF]

We report a 4-year-old girl presenting with progressive linear scleroderma affecting the right leg. Biopsy specimen disclosed typical histopathological findings of localized scleroderma. Right leg magnetic resonance imaging (MRI) showed high signal areas
Ogawa, Fumihide, Sueyoshi, Fumiko, Muroi, Eiji, Yamaoka, Toshifumi, Sato, Shinichi   +4 more
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Presentations and Treatment of Childhood Scleroderma: Localized Scleroderma, Eosinophilic Fasciitis, Systemic Sclerosis, and Graft-Versus-Host Disease

, 2011
Juvenile scleroderma is a rare connective tissue disease that involves the skin and subcutaneous tissue. Among all presentations of juvenile scleroderma, localized scleroderma (JLSc) is the most frequent, followed by systemic disease (JSSc) and ...
Barbara Fiebig, Meinolf Suttorp, Manfred Gahr, Christian Michael Hedrich, Gabriele Hahn   +4 more
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Congenital localized scleroderma

Objectives Juvenile localized scleroderma (JLS) usually has its onset during later childhood. This report describes the clinical and serologic features of six children with congenital localized scleroderma (CLS).
Zulian , F.
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