Results 71 to 80 of about 471,570 (210)
Aging Cell, Volume 25, Issue 9, September 2026.Hutchinson‐Gilford progeria syndrome (HGPS) is a premature aging disorder caused by a mutation in LMNA that produces the toxic progerin protein. In this study, an adenine base editor delivered via AAV9 achieved partial gene correction in HGPS mice when given at two weeks of age, partially rescuing bone structural and gene expression parameters and ...
Wayne A. Cabral +17 more
wiley +1 more source
Periostin in Mature Stage Localized Scleroderma
, 2017 Copyright © The Korean Dermatological Association and The Korean Society for Investigative Dermatology. Background: Periostin is a novel matricellular protein expressed in many tissues, including bone, periodontal ligament, and skin.
Park, Hyun-Sun +14 more
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No Evidence for Borrelia burgdorferi-Specific DNA in Lesions of Localized Scleroderma [PDF]
, 1995 A possible association of Borrelia burgdorferi with localized scleroderma is currently the focus of intense research and discussion. Skin biopsies from 30 patients with localized scleroderma (28 of the plaque type/morphea; two linear scleroderma) were ...
Meurer, Michael +5 more
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Clinical, Cosmetic and Investigational Dermatology, 2022 Jaishree Sharad Skinfiniti Aesthetic Skin and Laser Clinic, Mumbai, Maharashtra, IndiaCorrespondence: Jaishree Sharad, Skinfiniti Aesthetic Skin and Laser Clinic, 601, Prabhat Chambers, Khar West, S.V.Road, Mumbai, Maharashtra, 400052, India, Tel ...
Sharad J
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TRPA1 Regulates Fibrosis‐Associated Transcriptional Pathways in Human Lung Epithelial Cells
Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 3, September 2026.ABSTRACT Transient receptor potential ankyrin 1 (TRPA1) is a cation channel originally identified in lung fibroblasts and extensively studied in sensory neurons, where it is associated with pain and neurogenic inflammation. We and others have recently shown that TRPA1 is also expressed in lung epithelial cells and that its expression is regulated by ...
Leevi Halonen +5 more
wiley +1 more source
Juvenile Localized Scleroderma. Questions of Treatment
Вопросы современной педиатрии, 2020 Juvenile localized scleroderma (JLS) is a group of childhood diseases with the main symptom — skin and subcutaneous structures lesions, without any organ involvement. There is active (inflammatory) and fibrotic phase in development of JLS.
Rinat K. Raupov, Mikhail M. Kostik
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Multiple External Invasive Root Resorption and Calcification in Systemic Sclerosis—Case Report
International Endodontic Journal, Volume 59, Issue 9, Page 1963-1978, September 2026.ABSTRACT Aim There are few reports in the literature of multiple external invasive root resorption (EIRR) lesions in patients with systemic sclerosis (SSc), and an association between root resorption and SSc is not well established. We report the only case that comprehensively illustrates—with the combination of histopathology, cone beam computed ...
Jee‐Yun Leung +3 more
wiley +1 more source
Internal Involvement in Localized Scleroderma
Medicine, 1994 We studied 76 consecutive patients with localized scleroderma (morphea with or without linear scleroderma) and analyzed the frequency, prognosis, and predictors of internal involvement in a subset of 53 patients systematically investigated for the presence of such involvement.
L, Dehen +3 more
openaire +2 more sources
Pathogenesis and treatment modalities of localized scleroderma
, 2010 Localized scleroderma is a chronic inflammatory disease primarily of the dermis and subcutaneous fat that ultimately leads to a scar-like sclerosis of connective tissue.
Skaidra Valiukevičienė +2 more
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Dental care in scleroderma – What should we know about scleroderma?
, 2019 Scleroderma is a disease of the connective tissue that is characterized by autoimmune reactions, excess collagen deposition and vascular hyperactivity and phenomena. It can affect virtually anyone at any age although having a predisposition towards women
Theos, Papaefstathiou
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