Results 61 to 70 of about 15,405 (223)

Clinical Profile of Methotrexate-resistant Juvenile Localised Scleroderma

Acta Dermato-Venereologica, 2019
Methotrexate has demonstrated its efficiency for the treatment of juvenile localized scleroderma but some patients may be resistant. The aim of our study was to define the profile of such patients.
Juliette Hardy, Franck Boralevi, Stéphanie Mallet, Natalia Cabrera, Alexandre Belot, Alice Phan, Sébastien Barbarot, Audrey Duriez-Lasek, Christine Chiaverini, Thomas Hubiche, Emmanuel Mahé, Edouard Bégon, Emmanuelle Bourrat, Olivia Boccara, Hélène Aubert, Martine Grall Lerosey, Catherine Droitcourt, Maryam Piram, Juliette Mazereeuw-Hautier, Research Group of the French Society of Paediatric Dermatology (SDFP in French)   +19 more
doaj   +1 more source

Morphea Profunda with Tertiary Lymphoid Follicles: Description of Two Cases and Review of the Literature

Dermatopathology, 2022
Morphea profunda or subcutaneous (deep) morphea is a variant of localized morphea, characterized by one or more ill-defined, deep sclerotic plaque. Preferential sites are the abdomen, trunk, sacral area, or extremities.
Angelo Cassisa, Margherita Vannucchi
doaj   +1 more source

Cross-disease innate gene signature: Emerging diversity and abundance in RA comparing to SLE and SSc [PDF]

, 2019
Overactivation of the innate immune system together with the impaired downstream pathway of type I interferon-responding genes is a hallmark of rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), and systemic sclerosis (SSc).
Fillerová, Regina, Horák, Pavel, Kriegová, Eva, Kudělka, Miloš, Mrázek, František, Petráčková, Anna, Radvanský, Martin, Skácelová, Martina, Smržová, Andrea   +8 more
core   +1 more source

Janus Kinase Inhibitors for the Treatment of Pediatric Morphea: A Systematic Review

Pediatric Dermatology, EarlyView.
ABSTRACT Morphea, also known as localized scleroderma (LoS), is an inflammatory, fibrosing dermatologic disorder of the skin and underlying tissues with associated comorbidities including joint contractures, limb‐length discrepancies, and inflammatory arthropathy occurring more commonly in children.
Alexa Moschella, Celina DeBiasio, Carmen Liy‐Wong   +2 more
wiley   +1 more source

Acquired Strabismus in Linear Scleroderma of the Face

Acta Dermato-Venereologica, 2019
is missing (Short communication)
Giorgia Martini, Maria Elisabetta Zannin, Fiorella Rodeghiero, Sandro Dal Pos, Francesco Zulian   +4 more
doaj   +1 more source

Novel Combination of UVA‐1 Phototherapy With Topical Tofacitinib for Treating Eosinophilic Fasciitis With Morphea: Case Report

Pediatric Dermatology, EarlyView.
ABSTRACT Eosinophilic fasciitis (EF) and morphea are rare sclerosing connective tissue disorders, and there remains debate about whether these entities are pathologically distinct or related. This case report describes the successful treatment of an adolescent patient who developed progressive morphea plaques while being treated with systemic ...
Daphne M. Cheung, Ye‐Jean Park, Nadia Luca, Frankie Fraulin, Marie‐Anne Brundler, Michele Ramien   +5 more
wiley   +1 more source

SSB-1 of the yeast Saccharomyces cerevisiae is a nucleolar-specific, silver-binding protein that is associated with the snR10 and snR11 small nuclear RNAs [PDF]

, 1990
SSB-1, the yeast single-strand RNA-binding protein, is demonstrated to be a yeast nucleolar-specific, silver-binding protein. In double-label immunofluorescence microscopy experiments antibodies to two other nucleolar proteins, RNA Pol I 190-kD and ...
Abelson, John, Campbell, Judith, Clark, Michael W., Yip, Man Lun R.   +3 more
core   +2 more sources

Calcinosis Cutis and Delayed‐Onset Myositis in a Case of Suspected Localized Scleroderma: A Diagnostic and Therapeutic Challenge

Pediatric Dermatology, EarlyView.
ABSTRACT A 16‐year‐old girl presenting with calcinosis cutis and localized scleroderma subsequently developed delayed‐onset idiopathic inflammatory myopathy five years after initial skin involvement. Despite the absence of typical dermatomyositis features and negative myositis‐specific antibodies, whole‐body MRI revealed extensive subclinical muscle ...
Edoardo Marrani, Laura Gatti, Ilaria Pagnini, Teresa Oranges, Cesare Filippeschi, Gabriele Simonini   +5 more
wiley   +1 more source

Abdominopelvic post-irradiation morphea in a prostate cancer patient: the first case of an under recognized condition [PDF]

, 2015
NON
Di Meo, N., Noal, C., Trevisan, G., Trevisini, S., Ulessi, B.   +4 more
core   +1 more source

Progressive Hemifacial Atrophy with Morphea of Cheek

Journal of Indian Academy of Oral Medicine and Radiology, 2006
Scleroderma is a rare collagen disorder in which fibrosis of skin, subcutaneous tissues and muscles can occur with occasional involvement of bones. Localized scleroderma is a benign condition but can cause significant deformity when it affects the face ...
Ajit Auluck, Keerthilatha M Pai
doaj