Results 141 to 150 of about 1,415,478 (254)

A novel patient‐reported outcome for paediatric localized scleroderma: a qualitative assessment of content validity

open access: yesBritish Journal of Dermatology, 2019
According to current standards, no existing patient‐reported outcome (PRO) measures have high‐quality validity evidence for use with individuals diagnosed with paediatric localized scleroderma (LS).
C. Zigler   +4 more
semanticscholar   +1 more source

Oral complaints in progressive systemic sclerosis : two cases report [PDF]

open access: yes, 2008
Progressive systemic sclerosis is a chronic sclerotic disease which causes diffuse, increased deposition of extracellular matrix in connective tissue with vascular abnormalities, resulting in tissue hypoxia.
Cardoso, Álvaro Bezerra   +5 more
core  

Experience with Lipofilling in Children with Localized Scleroderma: Case Study

open access: yesВопросы современной педиатрии
Background. Localized scleroderma (LS) is an inflammatory sclerosing disease of unknown etiology. It is characterized by progressive lesion of connective tissue leading to sclerosis and/or atrophy of the skin and underlying tissues.
Alina R. Misbakhova   +4 more
doaj   +1 more source

Brain cavernomas associated with en coup de sabre linear scleroderma: Two case reports

open access: yesPediatric Rheumatology Online Journal, 2011
Linear scleroderma is a form of localized scleroderma that primarily affects the pediatric population. When it occurs on the scalp or forehead, it is termed "en coup de sabre".
Laxer Ronald M   +5 more
doaj   +1 more source

Prediction of disease relapse in a cohort of paediatric patients with localized scleroderma

open access: yesBritish Journal of Dermatology, 2018
Localized scleroderma (LS) is an autoimmune condition of the skin and underlying tissue. Active or recurring disease can lead to cumulative tissue damage, especially in paediatric‐onset disease.
K. Kurzinski, C. Zigler, K. Torok
semanticscholar   +1 more source

Topical application of a peptide inhibitor of transforming growth factor-beta1 ameliorates bleomycin-induced skin fibrosis [PDF]

open access: yes, 2005
Transforming growth factor-beta (TGF-beta) plays a crucial role in the pathogenesis of skin fibrotic diseases. Systemic TGF-beta inhibitors effectively inhibit fibrosis in different animal models; however, systemic inhibition of TGF-beta raises important
Borras-Cuesta, F. (Francisco)   +8 more
core  

Eosinophilic fasciitis--progression to linear scleroderma: a case report

open access: yesThe Turkish Journal of Pediatrics, 1999
Eosinophilic fasciitis is a rare disease in children. Although changes similar to linear scleroderma have been reported, the outcome is usually good. In this report, a 10-year-old boy who developed eosinophilic fasciitis without a good response to
A Balat   +4 more
doaj  

Optimal management strategies for paediatric morphea – insights from a case series

open access: yesPediatria Polska
Juvenile localized scleroderma, or morphea, is a rare chronic inflammatory disease primarily affecting the skin and subcutaneous tissue. Treatment options for paediatric cases are diverse, with a lack of standardised guidelines.
Kinga Łagosz   +6 more
doaj   +1 more source

DNA methylation patterns in juvenile systemic sclerosis and localized scleroderma.

open access: yesClinical Immunology, 2021
P. Coit   +4 more
semanticscholar   +1 more source

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