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Localized and systemic scleroderma
Seminars in Cutaneous Medicine and Surgery, 2001Scleroderma is a broad term encompassing both localized and systemic sclerosis. Localized scleroderma is a cutaneous limited fibrosis that manifests as plaque morphea, generalized morphea, linear scleroderma, and deep morphea. Systemic scleroderma (sclerosis) can manifest as either limited or diffuse disease.
A, Hawk, J C, English
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Localized scleroderma of the breast
European Radiology, 2001We report a 44-year-old patient with right-breast morphea. Mammography, MRI and needle biopsy were used for assessment of the case. Mammography demonstrated thickening of the skin and the subcutaneous tissue. The MRI showed replacement of the subcutaneous and breast fat by a low signal intensity, non-enhancing tissue.
Elisa, Operé +3 more
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Management of localized scleroderma
Seminars in Cutaneous Medicine and Surgery, 1998Localized scleroderma denotes a spectrum of conditions characterized by circumscribed fibrotic areas involving different levels of the dermis, subcutis, and sometimes underlying soft tissue and bone. Although the clinical course of the disease is often benign, widespread lesions and disabling joint contractures may lead to significant complications ...
N, Hunzelmann +3 more
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The Prognosis of Localized Scleroderma
Archives of Dermatology, 1958While much interest has been given to the generalized systemic forms of scleroderma, relatively little information has appeared about localized scleroderma. Reports concerning the use of various therapeutic agents in localized scleroderma continue to appear, but with a limited knowledge of the natural course of the untreated disease and often a lack of
A C, CURTIS, T G, JANSEN
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Seminars in Cutaneous Medicine and Surgery, 1998
Localized scleroderma can be divided into three main subtypes: morphea, linear scleroderma, and generalized morphea. Plaque morphea usually has a good prognosis. Variants of morphea, including guttate morphea and atrophoderma of Pasini and Pierini, are seen.
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Localized scleroderma can be divided into three main subtypes: morphea, linear scleroderma, and generalized morphea. Plaque morphea usually has a good prognosis. Variants of morphea, including guttate morphea and atrophoderma of Pasini and Pierini, are seen.
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Borrelia burgdorferi and localized scleroderma
Clinics in Dermatology, 1994L yme borreliosis is a multisystemic disorder caused by the spirochete Borrelia burgdorferi and transmitted by the Ixodes tick. The initial manifestations of the disease are the characteristic skin lesion, erythema migrans, and symptoms of general malaise (stage I).
TREVISAN, GIUSTO +2 more
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Archives of dermatology, 1975
Familial scleroderma is rare; only seven documented instances of the disease have been reported, to our knowledge. This report adds two more families to the literature. Three children in one family and two in the other had clinically and histiologically established localized scleroderma.
R C, Wuthrich, H H, Roenigk, W D, Steck
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Familial scleroderma is rare; only seven documented instances of the disease have been reported, to our knowledge. This report adds two more families to the literature. Three children in one family and two in the other had clinically and histiologically established localized scleroderma.
R C, Wuthrich, H H, Roenigk, W D, Steck
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Localized Scleroderma of the Face
2013Localized scleroderma (LS), also known as morphea, is the most frequent form of scleroderma in childhood and is grouped into five subtypes: circumscribed morphea, linear scleroderma, generalized morphea, pansclerotic morphea, and a mixed subtype, where a combination of two or more of the previous subtypes is present.
Zulian F, Trainito S, Belloni Fortina A
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Dermatologic therapy, 2012
Localized scleroderma (also called morphea) is a term encompassing a spectrum of sclerotic autoimmune diseases that primarily affect the skin, but also might involve underlying structures such as the fat, fascia, muscle, and bones. Its exact pathogenesis is still unknown, but several trigger factors in genetically predisposed individuals might ...
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Localized scleroderma (also called morphea) is a term encompassing a spectrum of sclerotic autoimmune diseases that primarily affect the skin, but also might involve underlying structures such as the fat, fascia, muscle, and bones. Its exact pathogenesis is still unknown, but several trigger factors in genetically predisposed individuals might ...
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Glycosaminoglycans in Localized Scleroderma (Morphoea)
Connective Tissue Research, 1985The composition of glycosaminoglycans (GAGs) was analyzed in skin samples of eight patients suffering from localized scleroderma, i.e., three having generalized morphoea and five localized morphoea plaques. From each patients, biopsies were obtained from sclerotic and perilesional areas, and from clinically uninvolved skin of the same region.
R, Møller, J, Serup, T, Ammitzbøll
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