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Localized Scleroderma of the Face
2013Localized scleroderma (LS), also known as morphea, is the most frequent form of scleroderma in childhood and is grouped into five subtypes: circumscribed morphea, linear scleroderma, generalized morphea, pansclerotic morphea, and a mixed subtype, where a combination of two or more of the previous subtypes is present.
Zulian F, Trainito S, Belloni Fortina A
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Archives of dermatology, 1975
Familial scleroderma is rare; only seven documented instances of the disease have been reported, to our knowledge. This report adds two more families to the literature. Three children in one family and two in the other had clinically and histiologically established localized scleroderma.
R C, Wuthrich, H H, Roenigk, W D, Steck
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Familial scleroderma is rare; only seven documented instances of the disease have been reported, to our knowledge. This report adds two more families to the literature. Three children in one family and two in the other had clinically and histiologically established localized scleroderma.
R C, Wuthrich, H H, Roenigk, W D, Steck
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Dermatologic therapy, 2012
Localized scleroderma (also called morphea) is a term encompassing a spectrum of sclerotic autoimmune diseases that primarily affect the skin, but also might involve underlying structures such as the fat, fascia, muscle, and bones. Its exact pathogenesis is still unknown, but several trigger factors in genetically predisposed individuals might ...
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Localized scleroderma (also called morphea) is a term encompassing a spectrum of sclerotic autoimmune diseases that primarily affect the skin, but also might involve underlying structures such as the fat, fascia, muscle, and bones. Its exact pathogenesis is still unknown, but several trigger factors in genetically predisposed individuals might ...
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Localized Scleroderma: A Clinical Review
Current Rheumatology Reviews, 2017Localized scleroderma (LS) is characterized by excessive collagen deposition leading to thickening of the dermis, subcutaneous tissue or both. The outcome for most patients with localized scleroderma is directly related to the type and stage of the affected tissue.
Mark, Tratenberg +5 more
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Morphea and localized scleroderma in children
Seminars in Cutaneous Medicine and Surgery, 1999Localized scleroderma refers to a diverse spectrum of disorders that involve fibrosis of the skin. Children are more likely than adults to develop localized forms of scleroderma. This condition may have devastating effects on growth and development such as limb asymmetry, flexion contractures, and psychological disability. The pathogenesis of localized
E, Vierra, B B, Cunningham
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Glycosaminoglycans in Localized Scleroderma (Morphoea)
Connective Tissue Research, 1985The composition of glycosaminoglycans (GAGs) was analyzed in skin samples of eight patients suffering from localized scleroderma, i.e., three having generalized morphoea and five localized morphoea plaques. From each patients, biopsies were obtained from sclerotic and perilesional areas, and from clinically uninvolved skin of the same region.
R, Møller, J, Serup, T, Ammitzbøll
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Archives of Dermatology, 1966
A case of linear and morphea scleroderma is reported. Histochemical studies revealed an increase of positive PAS material, diastase resistant, in the areas of homogenized collagen. Chemical analysis suggests an increase in hexoses and hexosamines, probably bound to the collagen fibers.
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A case of linear and morphea scleroderma is reported. Histochemical studies revealed an increase of positive PAS material, diastase resistant, in the areas of homogenized collagen. Chemical analysis suggests an increase in hexoses and hexosamines, probably bound to the collagen fibers.
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Borrelia burgdorferi and Localized Scleroderma
Archives of Dermatology, 1989To the Editor.— Aberer et al, 1 in Austria, have suggested that morphea might be related to Borrelia burgdorferi infection. These authors found antibodies to B burgdorferi in five of ten patients with morphea in one study and eight of 15 patients in another study, which used the enzyme-linked immunosorbent assay.
V, Lecerf +4 more
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