Results 131 to 140 of about 56,983 (273)
Exploring cellular changes in ruptured human quadriceps tendons at single‐cell resolution
The Journal of Physiology, EarlyView.Abstract figure legend This study explores the cellular landscape of healthy and ruptured quadriceps tendons using single nucleus RNA sequencing. While a range of stromal and immune cell types and subsets were identified, the data indicate that fibroblasts and endothelial cells are the main drivers of the early injury response within ruptured ...
Jolet Y. Mimpen +15 more
wiley +1 more source
Hematological Oncology, Volume 43, Issue 3, May 2025.ABSTRACT Localized light chain amyloidosis (loc‐AL) is a rare disorder characterized by localized deposition of misfolded AL fibrils. There are limited data on patterns of disease presentation and long‐term outcomes. In this study, we retrospectively reviewed 146 patients with loc‐AL at our institution between January 1, 2010, and March 1, 2024.
Danai Dima +11 more
wiley +1 more source
Diabetes, Obesity and Metabolism, Volume 27, Issue 5, Page 2601-2612, May 2025.Abstract Aims Individuals with liver insulin‐resistant (LIR) or muscle insulin‐resistant (MIR) phenotypes may respond differently to dietary interventions. Given the interaction between insulin resistance and cardiovascular risk, this sub‐analysis of the PERSON study examined whether a personalized diet according to MIR or LIR phenotypes improves ...
Lisa Wanders +8 more
wiley +1 more source
Osteoclastogenesis in Patients With Systemic Sclerosis With and Without Calcinosis Cutis
ACR Open Rheumatology, Volume 7, Issue 4, April 2025.Objective We aimed to assess whether the presence of radiographically confirmed calcinosis of the hands in patients with systemic sclerosis (SSc) is associated with increased osteoclastogenesis. Methods We recruited 20 patients with SSc (10 with calcinosis and 10 without calcinosis) and 10 age‐ and gender‐matched healthy controls. Hand radiographs were
Antonia Valenzuela +6 more
wiley +1 more source
Cerebrovascular Involvement in Systemic Sclerosis
ACR Open Rheumatology, Volume 7, Issue 4, April 2025.Systemic sclerosis (SSc) is a chronic autoimmune rheumatic disease characterized by vascular damage, immune system dysregulation and fibrosis. The hallmark features include microvascular alterations and progressive tissue fibrosis, affecting skin, internal organs as well central and peripheral nervous system, adding to the disease's complexity and ...
Maurizio Cutolo +4 more
wiley +1 more source
Risk of Raynaud's Phenomenon Among Workers in the Occupational Disease Surveillance System
American Journal of Industrial Medicine, Volume 68, Issue 4, Page 344-357, April 2025.ABSTRACT Introduction Raynaud's phenomenon (RP) is linked to occupational exposures such as vibration, cold temperature, and chemicals. However, large cohort studies examining RP by occupation and sex are scarce. To address this gap, this study aimed to assess risk of RP by both occupation and sex in a large cohort of workers in Ontario, Canada ...
Ryann E. Yeo +3 more
wiley +1 more source
Erratum to “From Localized Scleroderma to Systemic Sclerosis: Coexistence or Possible Evolution”
Dermatology Research and Practice, 2018 Dilia Giuggioli +5 more
doaj +1 more source
Arthritis &Rheumatology, Volume 77, Issue 4, Page 439-449, April 2025.Objective Nongenetic factors influence systemic sclerosis (SSc) pathogenesis, underscoring epigenetics as a relevant contributor to the disease. We aimed to unravel DNA methylation abnormalities associated with SSc through an epigenome‐wide association study. Methods We analyzed DNA methylation data from whole‐blood samples in 179 patients with SSc and
Javier Martínez‐López +19 more
wiley +1 more source