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Molecular ablation of transforming growth factor beta signaling pathways by tyrosine kinase inhibition: the coming of a promising new era in the treatment of tissue fibrosis. [PDF]
, 2008 Jimenez, Sergio A., Rosenbloom, Joel
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Scleroderma renal crisis associated with a complement‑related gene mutation： a case report
Linchuang shenzangbing zazhiDu Qiao-yue, Pan Feng-jun, Wu Wei
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Seminars in Arthritis and Rheumatism, 2015
To discuss the pathophysiology, risk factors, clinical manifestations, diagnosis, treatment, prevention, and outcomes of scleroderma renal crisis (SRC), a serious yet potentially treatable complication of scleroderma (systemic sclerosis).A PubMed search for articles published up until April 2014 was conducted using the following keywords: scleroderma ...
Nilanjana, Bose +2 more
+7 more sources
To discuss the pathophysiology, risk factors, clinical manifestations, diagnosis, treatment, prevention, and outcomes of scleroderma renal crisis (SRC), a serious yet potentially treatable complication of scleroderma (systemic sclerosis).A PubMed search for articles published up until April 2014 was conducted using the following keywords: scleroderma ...
Nilanjana, Bose +2 more
+7 more sources
La Presse Médicale, 2021
Scleroderma renal crisis (SRC) is a rare but life-threatening complication of systemic sclerosis (SSc) characterized by malignant hypertension and acute kidney injury. Historically, SRC was the leading cause of death in SSc. However, with the advent of angiotensin converting enzyme (ACE) inhibitors, mortality rates have decreased significantly ...
Marie Hudson +2 more
openaire +2 more sources
Scleroderma renal crisis (SRC) is a rare but life-threatening complication of systemic sclerosis (SSc) characterized by malignant hypertension and acute kidney injury. Historically, SRC was the leading cause of death in SSc. However, with the advent of angiotensin converting enzyme (ACE) inhibitors, mortality rates have decreased significantly ...
Marie Hudson +2 more
openaire +2 more sources
British Journal of Hospital Medicine, 2013
Systemic sclerosis is an autoimmune connective tissue disorder characterized by endothelial cell injury, vascular hyper-reactivity, obliterative microvasculopathy and excess collagen deposition, particularly within the dermis of the skin. Table 1 outlines the various terms that are used to describe the extent and location of sclerosis.
Tamer, Rezk +3 more
openaire +3 more sources
Systemic sclerosis is an autoimmune connective tissue disorder characterized by endothelial cell injury, vascular hyper-reactivity, obliterative microvasculopathy and excess collagen deposition, particularly within the dermis of the skin. Table 1 outlines the various terms that are used to describe the extent and location of sclerosis.
Tamer, Rezk +3 more
openaire +3 more sources
Scleroderma Renal Crisis Prior to Scleroderma
American Journal of Kidney Diseases, 1989SCLERODERMA renal crisis (SRC) is characterized by rapid onset of severe hypertension and rapid deterioration of renal function. Although this event usually complicates established progressive systemic sclerosis (PSS), occasionally SRC may be the mode of presentation of the illness.
S F, Gouge +4 more
openaire +2 more sources
Reumatizam, 2011
Systemic sclerosis (SSc) is a multisystem disease whose clinical manifestations result from inflammation, vascular injury and obliteration, and cutaneous and visceral fibrosis. Scleroderma renal crisis (SRC) occurs in 5% of patients with particullary diffuse form of SSc.
Jadranka, Morović-Vergles +2 more
openaire +3 more sources
Systemic sclerosis (SSc) is a multisystem disease whose clinical manifestations result from inflammation, vascular injury and obliteration, and cutaneous and visceral fibrosis. Scleroderma renal crisis (SRC) occurs in 5% of patients with particullary diffuse form of SSc.
Jadranka, Morović-Vergles +2 more
openaire +3 more sources
Histologic Features Associated with Kidney Survival in Scleroderma Renal Crisis.
Journal of the American Society of NephrologyBACKGROUND Scleroderma renal crisis is a severe complication of systemic sclerosis that is associated with higher morbidity and mortality. However, limited data are currently available regarding the factors affecting renal outcome during scleroderma ...
Yannick Binois +28 more
semanticscholar +1 more source
Rheumatology
OBJECTIVE To determine the prevalence and incidence of scleroderma renal crisis (SRC) in patients with systemic sclerosis (SSc) over two time periods and to identify factors influencing potential epidemiological changes.
Xavier Pla-Salas +35 more
semanticscholar +1 more source
OBJECTIVE To determine the prevalence and incidence of scleroderma renal crisis (SRC) in patients with systemic sclerosis (SSc) over two time periods and to identify factors influencing potential epidemiological changes.
Xavier Pla-Salas +35 more
semanticscholar +1 more source