Results 41 to 50 of about 1,931,520 (187)

Gender differences in organ involvement and survival in systemic sclerosis – experience of a EUSTAR center [PDF]

Romanian Journal of Rheumatology, 2021
Introduction. The low overall prevalence of systemic sclerosis (SSc) and the low proportion of male patients have resulted in a scarcity of studies assessing sex differences in SSc patients, and contradictory results have often been observed.
Laura Groseanu, Andreea Petre, Andra Balanescu, Violeta Bojinca, Daniela Opris-Belinski, Florian Berghea, Ioana Saulescu, Diana Mazilu, Sanziana Daia Iliescu, Andreea Borangiu, Cosmin Constantinescu, Claudia Cobilinschi, Maria Magdalena Negru, Mihai Abobului, Ruxandra Ionescu   +14 more
doaj   +1 more source

Scleroderma Renal Crisis Precipitated by Steroid Treatment in Systemic Lupus Erythematosus and Scleroderma Overlap Syndrome [PDF]

, 2012
Introduction: Connective tissue disorders can overlap in various ways. Patients may present with features of more than one specific disease without satisfying the diagnostic criteria and thereafter evolve into a specific disease entity.
Hamzi, AM, Benyahia, M, Alayoud, A, Qamouss, O, Oualim, Z   +4 more
core   +1 more source

A Role of Myocardin Related Transcription Factor-A (MRTF-A) in Scleroderma Related Fibrosis. [PDF]

, 2015
In scleroderma (systemic sclerosis, SSc), persistent activation of myofibroblast leads to severe skin and organ fibrosis resistant to therapy. Increased mechanical stiffness in the involved fibrotic tissues is a hallmark clinical feature and a cause of ...
Ayuko Takahashi (789901), Barbara D. Smith (2212672), Takahashi, A, Christopher Denton, Layne, MD, Bahja Ahmed-Abdi, Ayuko Takahashi, Suki, B, Nikitorowicz-Buniak, J, Bela Suki (2212681), Bahja Ahmed-Abdi (2212675), Matthew D. Layne (364786), Markella Ponticos, Ahmed-Abdi, B, Robert Lafyatis, Markella Ponticos (2212669), Xu Shiwen (2212678), Stratton, R, Bela Suki, Barbara D Smith, Richard Stratton (776213), Joanna Nikitorowicz-Buniak (776212), Smith, BD, Christopher Denton (276245), Xu Shiwen, Lafyatis, R, David Abraham (36404), Shiwen, X, David Abraham, Abraham, D, Matthew D Layne, Ponticos, M, Denton, C, Joanna Nikitorowicz-Buniak, Robert Lafyatis (38139), Richard Stratton   +35 more
core   +1 more source

Assessment of kidney involvement in systemic sclerosis: from scleroderma renal crisis to subclinical renal vasculopathy

, 2022
The spectrum of kidney involvement in systemic sclerosis (SSc) includes scleroderma renal crisis, widely recognized as the most severe renal-vascular complication, but also several forms of chronic renal vasculopathy and reduced renal function are ...
Giorgia Leodori, Antonietta Gigante, Chiara Pellicano, Edoardo Rosato, Annalisa Villa   +4 more
core   +1 more source

Cerebral infarction caused by systemic sclerosis: a case report

Journal of International Medical Research, 2021
Systemic sclerosis, also known as scleroderma, is a rare multisystem autoimmune disease characterized by vascular lesions caused by collagen deposition in the skin and viscera and damage to the endothelium.
Qingqing Wang, Mengen Zhang, Mingfeng Zhai, Zongyou Li   +3 more
doaj   +1 more source

Systemic sclerosis with renal crisis and pericardial effusion

Clinical Case Reports, 2020
Scleroderma renal crisis occurs in 10% of patients with systemic sclerosis carrying a poor prognosis. A kidney biopsy is consistent with thrombotic microangiopathy (TMA) with clinical findings discerning it from other TMAs.
Kalyan Prudhvi, Jayasree Jonnadula, Gurusaravanan Kutti Sridharan, Mary Dominguez   +3 more
doaj   +1 more source

Atypical rapid onset Scleroderma Renal Crisis (SRC) complicated with diffuse alveolar hemorrhage and pleuro-pericardial effusions in a patient with recently diagnosed breast cancer and a positive anti-RNA polymerase III Ab.: A case report

Respiratory Medicine Case Reports, 2018
Scleroderma associated Pulmonary–Renal Syndrome is a rare but severe complication with a poor prognosis and high mortality. A high index of suspicion is needed for early recognition of this potential complication in patients with systemic sclerosis and ...
Hazim Bukamur, Obadah Aqtash, Ibrahim Shahoub, Emhemmid Karem, Iheanyichukwu Ogu, Fuad Zeid   +5 more
doaj   +1 more source

Scleroderma Renal Crisis in a Case of Mixed Connective Tissue Disease Treated Successfully with Angiotensin-Converting Enzyme Inhibitors

Case Reports in Nephrology, 2021
Mixed connective tissue disease (MCTD) is a rheumatic disease syndrome with overlapping features of scleroderma, systemic lupus erythematosus, and polymyositis. An extremely rare but serious complication that can occur in MCTD is scleroderma renal crisis
Jomana Madieh, Iman Khamayseh, Alaa Hrizat, Abdurrahman Hamadah, Kamel Gharaibeh   +4 more
doaj   +1 more source

Patterns of renal pathology in Chinese patients with systemic sclerosis undergoing renal biopsy at a tertiary medical center

Journal of International Medical Research, 2020
Objective We investigated renal injury characteristics in Chinese patients with systemic sclerosis (SSc) who had undergone renal biopsy. Methods We searched the medical records of patients with SSc who were hospitalized at Peking Union Medical College ...
Xiao-yu Cao, He Liu, Dong Xu, Meng-tao Li, Qian Wang, Li Jiang, Yong Hou, Li-xiu Zhu, Xiao-feng Zeng   +8 more
doaj   +1 more source

Scleroderma renal crisis

Rheumatic Disease Clinics of North America, 1996
Renal crisis occurs in systemic sclerosis patients with rapidly progressive diffuse cutaneous thickening early in their disease. SRC is characterized by malignant hypertension, hyperreninemia, azotemia, microangiopathic hemolytic anemia, and renal failure. This complication, which in the past has been almost uniformly fatal, is now successfully treated
openaire   +3 more sources