Results 81 to 90 of about 1,931,520 (187)
Objective Somatic items used in depression assessments can potentially overlap with symptoms related to physical illness, including systemic sclerosis (SSc). No studies have looked at whether somatic depression items may be influenced by diffuse versus limited SSc disease subtypes, which are associated with varying degrees of symptom presentation.
Sophie Hu +110 more
wiley +1 more source
Scleroderma Renal Crisis: A Rare but Severe Complication of Systemic Sclerosis [PDF]
Scleroderma renal crisis (SRC) is a major complication in patients with systemic sclerosis (SSc). It is characterized by malignant hypertension and oligo/anuric acute renal failure.
Noël, Laure-Hélène +5 more
core +1 more source
Objective Early diffuse cutaneous systemic sclerosis (dcSSc) is associated with substantial disease‐specific mortality. Scleroderma‐specific autoantibodies (SSc‐Ab) may influence disease course, but their prognostic value in very early dcSSc remains unclear.
Marzieh Jamali +6 more
wiley +1 more source
We had the challenged to treat a 40-year-old female with Systemic Scleroderma who was showing unspecific symptoms. During her time at the hospital she rapidly develops renal dysfunction, associated with hypertension.
Maite Hurtado Uriarte +2 more
doaj +1 more source
Multiorgan fibrosis arises when chronic injury activates fibroblasts and remodels extracellular matrix, whose increasing stiffness sustains disease through mechanotransduction pathways. Bidirectional cellular‐matrix feedback operates across lung, heart, liver, and kidney.
Amedeo Lonardo, Ralf Weiskirchen
wiley +1 more source
Pharmacological mechanisms and physiologic effects of GLP‐1 receptor agonists relevant to peri‐endoscopic risk. ABSTRACT The global increase in obesity, type 2 diabetes mellitus (T2DM), and metabolic dysfunction‐associated steatotic liver disease (MASLD) has led to a higher use of glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) among patients ...
Junaid Beig +7 more
wiley +1 more source
UK Scleroderma Study Group (UKSSG) guidelines on the diagnosis and management of scleroderma renal crisis [PDF]
The UK Scleroderma Study Group developed guidelines on the diagnosis and management of scleroderma renal crisis (SRC) based on best available evidence and clinical experience.
Harber, M +5 more
core
NORMOTENSİVE RENAL CRISIS IN SCLERODERMA OVERLAPPED DERMATOMYOSITIS
Dermatomyositis (DM) is the nonsuppurative inflammation of the skeletal muscle with dermal rashes. One third of the cases have an overlapping connective tissue disease or malignancy may be accompanying in 10% of them.
Rıfkı EVRENKAYA +5 more
doaj
Challenges in diagnosis and treatment of scleroderma renal crisis (clinical case report)
The pathogenesis and diagnostic approaches to scleroderma renal crisis (SRC) – an acute “scleroderma kidney” – a severe and life-threatening complication of systemic sclerosis (SSc) characterized by high mortality, are discussed.
E. M. Mishina +3 more
doaj +1 more source
The biomimetic self‐assembly nanomedicine reversing atherosclerosis via senotherapy strategy. ABSTRACT The greatest challenge in atherosclerosis (AS) management lies in achieving lesion reversal, not merely slowing progression. Senescent cell accumulation—driven by continuous generation and apoptotic resistance—perpetuates plaque pathology and ...
Yuhan Tian +9 more
wiley +1 more source

