Results 81 to 90 of about 3,371 (182)

A Unique Presentation of Anti-RNA Polymerase III Positive Systemic Sclerosis Sine Scleroderma

open access: yesCase Reports in Rheumatology, 2016
Systemic sclerosis is a rare autoimmune disorder with a wide spectrum of clinical manifestations and a multitude of autoantibodies that are associated with it.
Cody M. Lee   +4 more
doaj   +1 more source

A Potential Novel Molecular Interaction in Bronchiolitis Obliterans Syndrome in Lung Transplantation Patients: The Role of SERPINA3 and Osteoprotegerin

open access: yesThe FASEB Journal, Volume 40, Issue 8, 30 April 2026.
Serum SERPINA3 levels were higher in BOS compared to non‐BOS patients. OPG and SERPINA3 positive cells colocalized with tryptase positive mast cells in airways from BOS lung tissue. OPG and SERPINA3 staining positively correlated in partially and completely obstructed airways.
Yanzhe Liu   +8 more
wiley   +1 more source

Profile of systemic sclerosis and associated renal involvement

open access: yesArchives of Medicine and Health Sciences, 2015
Background: Systemic sclerosis (SSc) patients are encountered in all parts of the world. Few Indian studies are found in the literature on this connective tissue disorder of unknown etiology.
Neehar Shanavas, Anup K Das
doaj   +1 more source

Prevalence and Risk Factors for Esophageal Strictures in Systemic Sclerosis

open access: yesACR Open Rheumatology, Volume 8, Issue 4, April 2026.
Objective Gastroesophageal reflux disease (GERD) affects up to 90% of patients with systemic sclerosis (SSc). Chronic esophageal acid exposure can result in complications including the formation of esophageal strictures (ES). Proton pump inhibitors can alter gastric acid pH and improve GORD symptoms; however, there have been no recent studies ...
Alannah Quinlivan   +13 more
wiley   +1 more source

Scleroderma renal crisis: a review for emergency physicians

open access: yes, 2019
Scleroderma renal crisis (SRC) remains a high-risk clinical presentation, and many patients require emergency department (ED) management for complications and stabilization. This narrative review provides an evidence-based summary of the current data for
Koyfman, Alex   +3 more
core   +1 more source

CURRENT VIEWS ON THE HETEROGENEITY OF RENAL INVOLVEMENTS IN PATIENTS WITH SYSTEMIC SCLEROSIS

open access: yesНаучно-практическая ревматология, 2015
Systemic sclerosis (SS), is an autoimmune connective tissue disease, the main clinical signs of which are due to disseminated microcirculatory disorders and fibrosis of the skin and viscera.
A. V. Gordeev   +3 more
doaj   +1 more source

Renal pathology and clinical associations in systemic sclerosis: a historical cohort study

open access: yesInternational Journal of General Medicine, 2019
Pantipa Tonsawan,1 Komkid Talabthong,1 Anucha Puapairoj,2 Chingching Foocharoen11Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand; 2Department of Pathology, Faculty of Medicine, Khon Kaen University, Khon Kaen ...
Tonsawan P   +3 more
doaj  

Intersticial pulmonary disease in patients with systemic sclerosis. Narrative review of the literature

open access: yesIatreia, 2017
Introduction: Systemic sclerosis is a chronic autoimmune disease, characterized by the triad of small vessel vasculopathy, immune system activation and increased deposits of extracellular matrix in the skin and internal organs.
Álvarez-Barreneche, María Fernanda   +2 more
doaj   +1 more source

Endothelial lesion and complement activation in patients with Scleroderma Renal Crisis

open access: yesBrazilian Journal of Nephrology, 2019
In kidney biopsies reviews, scleroderma renal crisis (SRC) is characterized by vascular endothelial injuries, C4d deposits on peritubular vessels, and acute and chronic injuries coexisting on the same biopsy.
Ney Arencibia Pérez   +5 more
doaj   +1 more source

A Case of Scleroderma Renal Crisis.

open access: yesNishi Nihon Hifuka, 1994
59歳の女性。13年来の汎発性強皮症(SSc)にて加療中著明な高血圧を呈し, 検査所見では血漿レニン活性高値を示し, 強皮症腎クリーゼ(SRC)と診断した。カプトプリル, フロセミド, ニフェジピンの併用投与を行ったが, 奏効せず, 急速に腎機能が低下し, 死の転帰をとった。腎の剖検所見では小葉間動脈の内膜の浮腫状肥厚を認め, アルシアン青染色で陽性を示し強皮症腎に特徴的な所見を呈したが, SRCにしばしば認められる血管壁のフィブリノイド壊死は認めなかった。SScにおける最も重篤な合併症としてのSRCを念頭に置き, 早期に発見して対応することの重要性を強調した。
MATSUMOTO, Shigeru   +4 more
openaire   +1 more source

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