Results 81 to 90 of about 1,931,520 (187)

Differential Item Functioning on the Patient Health Questionnaire 8 by Disease Subtype, Language, Sex, and Age Among People With Systemic Sclerosis: A Scleroderma Patient‐Centered Intervention Network Cohort Study

open access: yesArthritis Care &Research, Volume 78, Issue 9, Page 1140-1148, September 2026.
Objective Somatic items used in depression assessments can potentially overlap with symptoms related to physical illness, including systemic sclerosis (SSc). No studies have looked at whether somatic depression items may be influenced by diffuse versus limited SSc disease subtypes, which are associated with varying degrees of symptom presentation.
Sophie Hu   +110 more
wiley   +1 more source

Scleroderma Renal Crisis: A Rare but Severe Complication of Systemic Sclerosis [PDF]

open access: yes, 2009
Scleroderma renal crisis (SRC) is a major complication in patients with systemic sclerosis (SSc). It is characterized by malignant hypertension and oligo/anuric acute renal failure.
Noël, Laure-Hélène   +5 more
core   +1 more source

Scleroderma‐Specific Autoantibodies and Disease Trajectories in Early Systemic Sclerosis: Insights From a Single‐Center Prospective Registry

open access: yesACR Open Rheumatology, Volume 8, Issue 9, September 2026.
Objective Early diffuse cutaneous systemic sclerosis (dcSSc) is associated with substantial disease‐specific mortality. Scleroderma‐specific autoantibodies (SSc‐Ab) may influence disease course, but their prognostic value in very early dcSSc remains unclear.
Marzieh Jamali   +6 more
wiley   +1 more source

Scleroderma Renal Crisis Debute with Thrombotic Microangiopathy: A Successful Case Treated with Eculizumab

open access: yesCase Reports in Nephrology, 2018
We had the challenged to treat a 40-year-old female with Systemic Scleroderma who was showing unspecific symptoms. During her time at the hospital she rapidly develops renal dysfunction, associated with hypertension.
Maite Hurtado Uriarte   +2 more
doaj   +1 more source

Mechanobiological feedback loops and quantitative decision thresholds in organ fibrosis: Translational principles for antifibrotic therapy

open access: yesJournal of Cell Communication and Signaling, Volume 20, Issue 3, September 2026.
Multiorgan fibrosis arises when chronic injury activates fibroblasts and remodels extracellular matrix, whose increasing stiffness sustains disease through mechanotransduction pathways. Bidirectional cellular‐matrix feedback operates across lung, heart, liver, and kidney.
Amedeo Lonardo, Ralf Weiskirchen
wiley   +1 more source

GLP‐1 Receptor Agonists and Endoscopy: Understanding Gastric Stasis, Aspiration Risk, and Contemporary Peri‐Procedural Guidance

open access: yesChronic Diseases and Translational Medicine, Volume 12, Issue 3, Page 183-196, September 2026.
Pharmacological mechanisms and physiologic effects of GLP‐1 receptor agonists relevant to peri‐endoscopic risk. ABSTRACT The global increase in obesity, type 2 diabetes mellitus (T2DM), and metabolic dysfunction‐associated steatotic liver disease (MASLD) has led to a higher use of glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) among patients ...
Junaid Beig   +7 more
wiley   +1 more source

UK Scleroderma Study Group (UKSSG) guidelines on the diagnosis and management of scleroderma renal crisis [PDF]

open access: yes, 2016
The UK Scleroderma Study Group developed guidelines on the diagnosis and management of scleroderma renal crisis (SRC) based on best available evidence and clinical experience.
Harber, M   +5 more
core  

NORMOTENSİVE RENAL CRISIS IN SCLERODERMA OVERLAPPED DERMATOMYOSITIS

open access: yesTurkish Journal of Nephrology, 2019
Dermatomyositis (DM) is the nonsuppurative inflammation of the skeletal muscle with dermal rashes. One third of the cases have an overlapping connective tissue disease or malignancy may be accompanying in 10% of them.
Rıfkı EVRENKAYA   +5 more
doaj  

Challenges in diagnosis and treatment of scleroderma renal crisis (clinical case report)

open access: yesСовременная ревматология
The pathogenesis and diagnostic approaches to scleroderma renal crisis (SRC) – an acute “scleroderma kidney” – a severe and life-threatening complication of systemic sclerosis (SSc) characterized by high mortality, are discussed.
E. M. Mishina   +3 more
doaj   +1 more source

Pathological Mechanism‐Inspired Biomimetic Nano‐Senotherapy for Reversing Experimental Atherosclerosis in ApoE−/− Mice

open access: yesAdvanced Science, Volume 13, Issue 47, 24 August 2026.
The biomimetic self‐assembly nanomedicine reversing atherosclerosis via senotherapy strategy. ABSTRACT The greatest challenge in atherosclerosis (AS) management lies in achieving lesion reversal, not merely slowing progression. Senescent cell accumulation—driven by continuous generation and apoptotic resistance—perpetuates plaque pathology and ...
Yuhan Tian   +9 more
wiley   +1 more source

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