Results 81 to 90 of about 81,794 (294)

Primary sclerosing cholangitis

Best Practice & Research Clinical Gastroenterology, 2010
Primary sclerosing cholangitis (PSC) is a chronic bile duct disease leading to fibrotic biliary strictures and liver cirrhosis. The patient population is heterogeneous with regard to disease progression and the presence of co-morbidities, complicating the practical handling of patients as well as studies of pathogenetic mechanisms. The aetiology of PSC
Tom H, Karlsen, Erik, Schrumpf, Kirsten Muri, Boberg   +2 more
openaire   +5 more sources

Systemic and Local Adiposity in the Bone Marrow Microenvironment Associated With Improved Prognosis in Hodgkin Lymphoma: Imaging and Molecular Analysis

International Journal of Cancer, EarlyView.
Schematic overview of systemic and bone marrow‐specific adiposity in Hodgkin Lymphoma (HL). Body Mass Index was associated with bone marrow (BM) involvement, relapse, and mortality (1). In contrast, increased yellow marrow density was associated with poorer prognosis (2).
Andreia Matos, William P. Cawthorn, Joana Marinho‐Dias, Sofia Ramalheira, Susana Roncon, Dulcineia Pereira, Teresa Ribeiro, Carla Rodrigues, Mário Mariz, Ana Miranda, Helena Brízido, Manuel Bicho, Pedro Medeiros, Ana Carneiro, Fernanda Trigo, Pingzhao Hu, Flávia Pereira, Hugo Duarte, Calum D. Gray, Tom Macgillivray, Alan G. Ramsay, Maria J. Oliveira, Ricardo Ribeiro   +22 more
wiley   +1 more source

Pelvic venous disorders in women: Diagnosis and management for gynecologists

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Pelvic venous disorders (PeVD) are an underrecognized yet significant cause of chronic pelvic pain (CPP) in reproductive‐aged women, characterized by venous reflux, obstruction, or both. This clinical opinion provides a practical overview of PeVD for gynecologists, outlining its pathophysiology, common presentations, diagnostic approach, and ...
Tiffany Ni, Inbar Friedman, Jessica Smith, Brian Liu, Mary Melchior, Andrew D. Brown   +5 more
wiley   +1 more source

Sclerosing Peritonitis: A Rare but Fatal Complication of Peritoneal Inflammation

Mediators of Inflammation, 2012
Sclerosing peritonitis is a rare form of peritoneal inflammation with an often fatal outcome. The major risk factor of sclerosing peritonitis is peritoneal dialysis treatment but it can also occur following renal or liver transplantation or be associated
Monika Merkle, Markus Wörnle
doaj   +1 more source

Ivermectin for onchocercal eye disease (river blindness).

, 2012
BACKGROUND: It is believed that ivermectin (a microfilaricide) could prevent blindness due to onchocerciasis. However, when given to everyone in communities where onchocerciasis is common, the effects of ivermectin on lesions affecting the eye are ...
Ejere, Henry OD, Evans, Jennifer R, Schwartz, Ellen, Wormald, Richard   +3 more
core   +1 more source

Can malignant and inflammatory pleural effusions in dogs be distinguished using computed tomography [PDF]

, 2017
Computed tomography (CT) is the primary imaging modality used to investigate human patients with suspected malignant or inflammatory pleural effusion, but there is a lack of information about the clinical use of this test in dogs.
Aquino, Bedford, Benamore, Caivano, Ceribasi, Charney, D'Angelo, Dempsey, Dubielzig, Echandi, Fossum, Gumber, Hirsch, Hung, Kawashima, Lara-Garcia, Metintas, Morrison, Mott, Müller, Nakamura, Prather, Przeździecki, Rebar, Reetz, Sahin, Smith, Swinbourne, Thrall, Traill, Tyler, Vansteenkiste, Vogtli, Waite, Wang, Yamamoto   +35 more
core   +1 more source

N6‐Methyladenosine (m6A) in Liver Disease: Pathogenic Mechanisms and Therapeutic Potential

iNew Medicine, EarlyView.
ABSTRACT Accumulating evidence highlights the critical role of epigenetic modifications, particularly N6‐methyladenosine (m6A), in liver disease. As the most abundant RNA modification in eukaryotic cells, m6A is dynamically regulated by multicomponent m6A methyltransferases (e.g., METTL3 and METTL14), demethylases (FTO and ALKBH5), and m6A‐binding ...
Yingfen Chen, Ru Ya, Ziling Zhang, Siyue Dong, Seol Hee Park, Wonhyo Seo, Yong He   +6 more
wiley   +1 more source

Rapid Progression of Primary Sclerosing Cholangitis Complicated with Ulcerative Colitis

Case Reports in Gastrointestinal Medicine, 2015
Primary sclerosing cholangitis is a cholestatic condition with unknown etiology and long-standing, progressive course, leading to cirrhosis and requiring orthotropic liver transplant. In approximately 80%, primary sclerosing cholangitis is accompanied by
Piotr Pardak, Ewa Walczak, Rafał S. Filip   +2 more
doaj   +1 more source

Clinical Features and Risk Factors of Autoimmune Liver Involvement in Pediatric Inflammatory Bowel Disease [PDF]

, 2016
OBJECTIVES:Autoimmune liver disease is reported in up to 7.8% of children with inflammatory bowel disease. A distinct inflammatory bowel disease phenotype has been suggested in adults and in small pediatric cohorts.
Alexopoulou, Alvarez, Block, Boonstra, Deneau, Dotson, Faubion, Feldstein, Goyal, Gregorio, Halliday, Hirschfield, Hov, Jose, Jose, Levine, Levine, Liberal, Loftus, Loftus, Lundqvist, Maggiore, Malaty, Mieli-Vergani, Navaneethan, Noble-Jamieson, Olsson, Ordonez, Penna, Rönnblom, Sokol, Zholudev   +31 more
core   +1 more source

Validation of a Multiparametric, Automated, Macroarray‐Based Assay for the Detection of Autoantibodies in Autoimmune Liver Disease

Journal of Clinical Laboratory Analysis, EarlyView.
The assay exploited a multiparametric and fully automated device applied to CHORUS EVO to validate that the CHORUS Macroarray Liver Diseases kit is a novel procedure for detecting autoantibodies of AIH and PBC. The assay resulted as linear, accurate, sensitive, specific, and able to distinguish between PBC and AIH.
Luigi Raganelli, Tommaso Bandini, Matilde Ilacqua, Helena Cerutti, Alessandra Cartocci, Giulia Tesi, Andrea Ianniello, Thomas Massari, Mirko Berretti, Roberto Centini, Michele Norelli, Alessandra Brogi, Giampaola Pesce, Danilo Villalta, Brunetta Porcelli   +14 more
wiley   +1 more source