Results 91 to 100 of about 6,713,973 (267)

Orthotopic liver transplantation in the mouse [PDF]

open access: yes, 1991
Demetris, AJ   +4 more
core   +2 more sources

Adjustment of Surveillance Intervals for Ulcerative Colitis‐Associated Neoplasia Based on Disease Duration

open access: yesDigestive Endoscopy, EarlyView.
ABSTRACT Objectives The risk of colitis‐associated cancer increases with disease duration in ulcerative colitis (UC), yet surveillance colonoscopy protocols generally stratify risk uniformly for patients with disease lasting over 8 years. This study evaluated whether shorter surveillance intervals might enhance lesion detection rates in patients with ...
Ryoya Sakakibara   +13 more
wiley   +1 more source

Vendor‐Agnostic Vision Transformer‐Based Artificial Intelligence for Peroral Cholangioscopy: Diagnostic Performance in Biliary Strictures Compared With Convolutional Neural Networks and Endoscopists

open access: yesDigestive Endoscopy, EarlyView.
ABSTRACT Objectives Accurate diagnosis of biliary strictures remains challenging. This study aimed to develop an artificial intelligence (AI) system for peroral cholangioscopy (POCS) using a Vision Transformer (ViT) architecture and to evaluate its performance compared to different vendor devices, conventional convolutional neural networks (CNNs), and ...
Ryosuke Sato   +15 more
wiley   +1 more source

Autoimmunity in MASLD: Focus on autoantibodies, anti‐apolipoprotein A1 IgG and G protein‐coupled receptors

open access: yesEuropean Journal of Clinical Investigation, EarlyView.
This review outlines the potential role of anti‐GPCR autoantibodies in MASLD/MASH, given their involvement in a wide range of diseases and their possible contribution to MASLD/MASH pathophysiology. We also focused on anti‐ApoA1 autoantibodies, sharing functional features with anti‐GPCR autoantibodies and have been shown to promote liver steatosis in ...
Sabrina Pagano   +3 more
wiley   +1 more source

Branched‐chain amino acids and all‐cause mortality in patients with liver cirrhosis, and the onset of diabetes in liver transplant recipients

open access: yesEuropean Journal of Clinical Investigation, EarlyView.
Our study demonstrates that total BCAA levels increase following liver transplantation. In patients with cirrhosis, higher total BCAA levels are associated with a reduced risk of all‐cause mortality. However, while this association is not observed in liver transplant recipients, elevated total BCAA levels are strongly linked to an increased risk of new‐
Yakun Li   +9 more
wiley   +1 more source

Multi‐omic analysis identifies biological processes underlying progressive interstitial lung disease in systemic sclerosis

open access: yesThe FEBS Journal, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease, and lung complications (ILD) are the main cause of death. This study compared SSc patients with and without lung disease to healthy volunteers. We found increased inflammation, specific proteins, and higher triglyceride levels linked to lung disease progression. These findings suggest triglycerides
Selena Bouffette   +16 more
wiley   +1 more source

Effect of Tirzepatide Treatment on Hepatic Biomarkers in Patients With Metabolic Dysfunction‐Associated Steatotic Liver Disease and Type 2 Diabetes Mellitus

open access: yesHepatology Research, EarlyView.
This study evaluated the effects of tirzepatide in patients with Type 2 diabetes mellitus and metabolic dysfunction‐associated steatotic liver disease. After 48 weeks of treatment, patients showed significant improvements in liver steatosis and injury, surrogate markers of liver fibrosis, glycemic control, and body weight. ABSTRACT Aim This study aimed
Taeang Arai   +20 more
wiley   +1 more source

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