Results 71 to 80 of about 7,904,350 (238)

Rare Variants in PFIC‐Related Genes Among Adults With Intrahepatic Cholestasis

Hepatology Research, EarlyView.
ABSTRACT Aim Biallelic pathogenic variants in progressive familial intrahepatic cholestasis (PFIC)‐related genes cause severe pediatric cholestasis. However, the clinical significance of heterozygous variants in adult intrahepatic cholestasis remains unclear.
Shunji Hirose, Kota Tsuruya, Yusuke Mishima, Yoshitaka Arase, Koichi Shiraishi, Vu Thi Hao, Satsuki Ieda, Masayuki Tanaka, Sanae Isaki, Tatehiro Kagawa   +9 more
wiley   +1 more source

Validating the 2022 WHO classification in thyroid carcinomas: Prospective evidence for predicting iodine resistance

Histopathology, EarlyView.
This study assessed the 2022 WHO classification for predicting RAIR disease in thyroid carcinomas, comparing it to older classifications. In a retrospective study of 253 cases, we found the 2022 classification more effective, especially by identifying high‐grade carcinomas and tumour necrosis as critical predictive factors.
Elise André, Laurine Mebarki, Mirela Ilie, Fabien Subtil, Claire Bournaud, Françoise Borson‐Chazot, Françoise Descotes, Jean‐Christophe Lifante, Mireille Bertholon‐Grégoire, Hélène Lasolle, Myriam Decaussin‐Petrucci   +10 more
wiley   +1 more source

World Health Organization classification of tumours of the breast 6th edition 2026

Histopathology, EarlyView.
The 6th edition of the World Health Organization Classification of Breast Tumours introduces changes based on recent advances in our understanding of breast biology, developments in diagnostic modalities, identification of specific molecular targets and new treatment regimes.
Cecily Quinn, Puay Hoon Tan, Kimberly H Allison, Edi Brogi, Sunil R Lakhani, Stuart J Schnitt, Stephen B Fox, Shabnam Jaffer, Aysegul Sahin, Roberto Salgado, Anna Sapino, Ernest Kwasi Adjei, Katherine Geiersbach, Thomas H Helbich, Matteo Lambertini, Christos Sotiriou, Jennelle C Hodge, Joseph D Khoury, Bharat Rekhi, Ales Ryska, Gary Tse, Andrew Field, Harshima Wijesinghe, Pavitratha Puspanathan, Christine Giesen, Blanca Iciar Indave Ruiz, Ian Ellis, Dilani Lokuhetty, WCT Standing Editorial Board, Wendy Cooper, Michael Eden, Andrew Field, Vicky Goh, Jennelle C. Hodge, James Kench, Joseph D. Khoury, Katia Leite, Zhiyong Liang, Daichi Maeda, George Netto, Bharat Rekhi, Miguel Reyes Mugica, Brian Rous, Ales Ryska, Shahin Sayed, Antonia Sepulveda, Chanjuan Shi, Gary Tse   +47 more
wiley   +1 more source

Small Extracellular Vesicle‐Associated Polymeric Immunoglobulin Receptor in Primary Liver Cancer: From Immunological Mediator to Oncogenic Driver and Biomarker

Cell Proliferation, EarlyView.
Jeremy Ting Ruei Hsu, Samuel Wan Ki Wong, Judy Yam Wai Ping   +2 more
wiley   +1 more source

A prospective study of 12‐month survival of patients with cirrhosis admitted to intensive care

Internal Medicine Journal, EarlyView.
Abstract Background The assessment on whether to escalate care in patients with cirrhosis to the intensive care unit (ICU) is complex, with little data on long‐term outcomes. The primary aim of this study was to prospectively examine the ability of liver‐specific and ICU prognostic scores to predict 12‐month survival among patients with cirrhosis in ...
Minnie Au, Xian J Mah, Sern W Yeoh, Anh D Pham, Ashley Bloom, Nina Parthasarathy, Stephen D Bloom, Rohit Sawhney, Peter Oziemski, Amanda J Nicoll   +9 more
wiley   +1 more source

INJECTION TREATMENT OF VARICOSE VEINS.: (1) A NEW SYRINGE FOR INJECTING SCLEROSING SOLUTIONS INTO VARICOSE VEINS

, 1928
A. A. Miller
semanticscholar   +1 more source

Senescent Human Liver Endothelial Cells Mediate CD4+ T Cell Recruitment via ICOSL

Immunology, EarlyView.
In this study, we detect senescent endothelial cells within chronically diseased human liver tissues. Next, we develop a novel protocol for the induction of paracrine senescence in primary human liver endothelial cells and explore their functionality.
Daniel A. Patten, Amy Lumley, Alex L. Wilkinson, Ayla O’Keeffe, Kelvin Yin, Niranjan Shirgaonkar, Ran Gao, Ramanuj DasGupta, Matthew Hoare, Shishir Shetty   +9 more
wiley   +1 more source

Five‐Year Outcomes and Disease Trajectories in Moderate‐to‐Severe Ulcerative Colitis: A Korean Multicenter Inception Cohort

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Background and Aim The incidence of ulcerative colitis (UC) has been increasing in Asia. Comprehensive data on the long‐term course of moderate‐to‐severe UC remain scarce. This study investigated the clinical outcomes and factors associated with a disabling disease course in Korean patients with moderate‐to‐severe UC.
Byong Duk Ye, Hyo Jong Kim, Dong Il Park, Young Sook Park, Kang‐Moon Lee, Jong Pil Im, Sung‐Ae Jung, Yoon Tae Jeen, Jae Myung Cha, Jae Hee Cheon, Sung Noh Hong, Youngdoe Kim, Jong Min Choi, YoungJa Lee, Chang Kyun Lee   +14 more
wiley   +1 more source

Primary sclerosing cholangitis in a cohort of South African petients with inflammatory bowel disease at Charlotte Maxeke Johannesburg Academic Hospital

, 2018
A research report submitted to the Faculty of Health Sciences, University of Witwatersrand, in fulfilment of the requirements for the degree of Master of Medicine in the branch of Internal Medicine.
Alshmandi, Mohamed Almokhtar Mohamed
core  

Recent advances in diagnosis and management of chronic cholestatic liver diseases: expert consensus

Chronic cholestatic liver diseases (CCLD), primarily including primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC), are characterized by impaired bile flow, leading to systemic complications such as pruritus, jaundice, fat soluble ...
Mukewar, Shrikant
core   +1 more source