Results 71 to 80 of about 6,753 (222)

Pre‐RAI Monocyte‐to‐Lymphocyte Ratio Predicts Early and Higher Recurrence Risk in Intermediate‐Risk DTC, While PNI and NRI Show No Prognostic Value

Clinical Endocrinology, EarlyView.
ABSTRACT Objective Differentiated thyroid carcinoma (DTC) has an excellent prognosis, but recurrence remains a clinical concern, especially in intermediate‐risk patients. Current stratification systems focus primarily on tumor characteristics, overlooking the host's biological capacity to counteract tumor progression.
Tommaso Piticchio, Francesco Galeano, Salvatore Volpe, Antonio Prinzi, Ignazio Barca, Andrea Scuto, Rosario Le Moli, Giulio Geraci, Andrea Tumminia, Sium Wolde Sellasie, Francesco Pallotti, Francesco Frasca   +11 more
wiley   +1 more source

Comparative Analysis of Incidental and Non‐Incidental Papillary Thyroid Microcarcinoma Outcomes: Implications on Management Recommendations

Clinical Endocrinology, EarlyView.
ABSTRACT Introduction Papillary thyroid microcarcinomas (PTMC) are defined by the World Health Organisation (WHO) as tumours measuring ≤ 10 mm. Incidental PTMCs, or lesions discovered postoperatively on histological examination, are less extensively studied compared with lesions diagnosed preoperatively through cytology, particularly in terms of ...
Emma A. Finnegan, Justin M. Hintze, Anne McGowan, James Gibney, Conall W. R. Fitzgerald, John Kinsella, Marie Louise Healy   +6 more
wiley   +1 more source

Desmoplastic Cutaneous Squamous Cell Carcinoma Is an Aggressive and Potentially Fatal Skin Cancer: A Systematic Review

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT The incidence and mortality of cutaneous squamous cell carcinoma (cSCC) are increasing. Desmoplastic cSCC (dcSCC) is an uncommon yet highly aggressive variant which has received relatively little attention in the literature. No systematic reviews of dcSCC are currently available.
Andrew Dettrick, Haris Mohammed, Thomas Hardman, Nicole Buddle, Ryan Livingston, Duncan Lambie, Rebecca Donkin   +6 more
wiley   +1 more source

A Rare Case of Cutaneous Extramedullary Hematopoiesis in Chronic Myeloid Leukemia

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Cutaneous extramedullary hematopoiesis (CEH) is a rare manifestation of extramedullary hematopoiesis (EMH), a process typically associated with fetal development or myeloproliferative neoplasms. EMH most commonly involves the spleen, liver, and lymph nodes, with CEH being exceedingly rare in chronic myeloid leukemia (CML).
Bennett Christie‐Nguyen, Hanadi El Achi, Levani Iashvili, Amer Wahed, Brenda Mai, Jacob Armstrong   +5 more
wiley   +1 more source

A Two‐Dimensional Plot of Cell Aggregates and Their Largest Nuclei Distinguishes Benign From Malignant Pleural Effusion Cytology Specimens

Cytopathology, EarlyView.
Scatter plots from all cases were categorized into four plot types. Cytologically negative cases mainly exhibited Small cluster (S‐type) and Horizontal (H‐type) patterns, whereas cytologically positive cases predominantly showed Vertical (V‐type) and Diagonal (D‐type) patterns.
Rio Kaneko, Sayaka Kobayashi, Hayato Ikota, Rio Shibanuma, Yoshimi Nishijima, Takeshi Hisada, Hideaki Yokoo, Masanao Saio   +7 more
wiley   +1 more source

Moderate increase of MET in hepatocytes protects against cholestatic liver injury by promoting an effective antioxidant response

The FEBS Journal, EarlyView.
Moderate overexpression of wild‐type Met in hepatocytes (Alb‐R26Met mouse model) boosts a strong antioxidant response dependent on the glutathione system while impairing TGF‐β signaling in the liver. This leads to improved liver regeneration and protects against DDC‐induced injury, a model for cholestatic disease sharing features with primary ...
Carlos González‐Corralejo, Juan García‐Sáez, María Figueroa‐Fuentes, Annalisa Addante, Cesáreo Roncero, Nerea Lazcanoiturburu, Beatriz Pacheco, Julián Sanz, Cristina Gato, Eva Fernández‐Calderón, María de la O López, Águeda González‐Rodríguez, Almudena Porras, Flavio Maina, Isabel Fabregat, Blanca Herrera, Aránzazu Sánchez   +16 more
wiley   +1 more source

Chronic ulcerative oesophagitis rich in IgG4‐positive plasma cells – a distinct clinicopathological entity

Histopathology, EarlyView.
We report a series of 12 patients (mean age 63 years) with chronic oesophageal ulceration showing morphological features of IgG4‐related inflammatory disease. Most patients underwent several rounds of endoscopy until this association was recognized. The majority of patients went into clinical and histological remission following corticosteroid therapy.
Hanna Henzinger, Ian Brown, Anthony J Gill, Tomas Slavik, Giuseppe Zamboni, Cord Langner   +5 more
wiley   +1 more source

Validating the 2022 WHO classification in thyroid carcinomas: Prospective evidence for predicting iodine resistance

Histopathology, EarlyView.
This study assessed the 2022 WHO classification for predicting RAIR disease in thyroid carcinomas, comparing it to older classifications. In a retrospective study of 253 cases, we found the 2022 classification more effective, especially by identifying high‐grade carcinomas and tumour necrosis as critical predictive factors.
Elise André, Laurine Mebarki, Mirela Ilie, Fabien Subtil, Claire Bournaud, Françoise Borson‐Chazot, Françoise Descotes, Jean‐Christophe Lifante, Mireille Bertholon‐Grégoire, Hélène Lasolle, Myriam Decaussin‐Petrucci   +10 more
wiley   +1 more source

Dental Undergraduate Student Stress, Anxiety and Confidence in Endodontic Education: A Narrative Review

International Endodontic Journal, EarlyView.
ABSTRACT Background Endodontics is considered a challenging and stressful area by dental practitioners and particularly by dental undergraduate students. Stress or anxiety is prevalent among dental undergraduates, with academic and clinical factors considered the principal sources.
K. J. Fouillen, H. F. Duncan, V. Chevalier   +2 more
wiley   +1 more source

Annual magnetic resonance cholangiopancreatography surveillance outcomes in individuals with primary sclerosing cholangitis

Internal Medicine Journal, EarlyView.
Abstract Background Annual surveillance for cholangiocarcinoma using magnetic resonance cholangiopancreatography (MRCP) has been recommended in primary sclerosing cholangitis (PSC) to improve the associated dismal outcomes. However, data are limited. Aims To compare the outcomes of surveillance versus non‐surveillance in patients with PSC.
Gary Dezhi Zhang, Chloe Attree, Nazneen Irani, Jonathan Tibballs, John Ferguson, Luis Calzadilla Bertot, Michael Wallace, Briohny Smith, George Garas, Gary Jeffrey, Leon Anton Adams, Gerry MacQuillan   +11 more
wiley   +1 more source