Results 51 to 60 of about 3,562 (214)
Hepatology Research, EarlyView.Zinc deficiency is frequently seen in patients with chronic liver disease and is linked to poor appetite and nutritional status. We found that switching to zinc histidine hydrate increased zinc levels within a short period and was associated with improved appetite.
Yoshihito Uchida +9 more
wiley +1 more source
Hepatology Research, EarlyView.Levels of anti‐integrin αvβ6 antibodies were significantly higher in pediatric‐onset primary sclerosing cholangitis (PSC) than in autoimmune hepatitis (AIH) and may reflect disease activity. These antibodies may serve as a novel biomarker for distinguishing PSC from AIH and for monitoring disease progression.
Yukako Maeda +17 more
wiley +1 more source
Rare Variants in PFIC‐Related Genes Among Adults With Intrahepatic Cholestasis
Hepatology Research, EarlyView.ABSTRACT Aim Biallelic pathogenic variants in progressive familial intrahepatic cholestasis (PFIC)‐related genes cause severe pediatric cholestasis. However, the clinical significance of heterozygous variants in adult intrahepatic cholestasis remains unclear.
Shunji Hirose +9 more
wiley +1 more source
Pemafibrate Improves Cholestatic Markers Regardless of the Presence of Primary Biliary Cholangitis
Hepatology Research, EarlyView.Pemafibrate improves liver function markers related to bile flow in primary biliary cholangitis (PBC), but whether this effect is disease‐specific remains unclear. In this study, pemafibrate reduced these markers in patients with and without PBC, suggesting broader effects on bile flow beyond PBC.
Ryohei Tanigawa +5 more
wiley +1 more source
Histopathology, EarlyView.The TESST classification of testicular sex cord‐stromal tumours was agreed upon by consensus based on the best available evidence. The picture shows the members of the TESST group and delegates of GUPS and ISUP present in‐person at the first meeting of the group held at Johns Hopkins Hospital (Baltimore, 2024). Aims Testicular sex cord‐stromal tumours (
Andres M. Acosta +29 more
wiley +1 more source
A prospective study of 12‐month survival of patients with cirrhosis admitted to intensive care
Internal Medicine Journal, EarlyView.Abstract Background The assessment on whether to escalate care in patients with cirrhosis to the intensive care unit (ICU) is complex, with little data on long‐term outcomes. The primary aim of this study was to prospectively examine the ability of liver‐specific and ICU prognostic scores to predict 12‐month survival among patients with cirrhosis in ...
Minnie Au +9 more
wiley +1 more source
Senescent Human Liver Endothelial Cells Mediate CD4+ T Cell Recruitment via ICOSL
Immunology, EarlyView.In this study, we detect senescent endothelial cells within chronically diseased human liver tissues. Next, we develop a novel protocol for the induction of paracrine senescence in primary human liver endothelial cells and explore their functionality.
Daniel A. Patten +9 more
wiley +1 more source
Journal of Gastroenterology and Hepatology, EarlyView.ABSTRACT Background and Aim The incidence of ulcerative colitis (UC) has been increasing in Asia. Comprehensive data on the long‐term course of moderate‐to‐severe UC remain scarce. This study investigated the clinical outcomes and factors associated with a disabling disease course in Korean patients with moderate‐to‐severe UC.
Byong Duk Ye +14 more
wiley +1 more source
Journal of Gastroenterology and Hepatology, EarlyView.ABSTRACT Introduction Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and sodium‐glucose cotransporter‐2 inhibitors (SGLT2is) have demonstrated cardiovascular and metabolic benefits individually; however, the comparative effectiveness of combination therapy versus monotherapy in patients with metabolic dysfunction‐associated steatotic liver ...
Mohanad A. Alkuwaiti +11 more
wiley +1 more source