Results 51 to 60 of about 2,753,748 (240)

N6‐Methyladenosine in Inflammatory Bowel Disease: An Emerging Regulator of Pathogenesis and a Novel Therapeutic Frontier

open access: yesiMetaMed, EarlyView.
Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the intestine associated with an imbalance in intestinal homeostasis. m6A‐modifying enzymes, consisting of m6A writers, erasers and readers, plays a pivotal role in the pathogenesis and progression of IBD by affecting four intestinal barriers, including the intestinal mechanical ...
Jiaxian Guo   +4 more
wiley   +1 more source

Impact of cystic fibrosis transmembrane conductance regulator modulator therapies on liver stiffness and liver enzymes: An observational perspective single‐center cohort study

open access: yesJPGN Reports, EarlyView.
Abstract Objectives The efficacy of cystic fibrosis transmembrane conductance regulator (CFTR)‐modulator therapies in preventing or ameliorating cystic fibrosis liver disease (CFLD) by correcting CFTR in cholangiocytes is not well‐documented. This study aimed to assess liver function during CFTR‐modulators.
Laura Giugliano   +12 more
wiley   +1 more source

Use of single‐use ultra‐slim endoscopes for evaluation of pediatric esophageal varices: A pilot feasibility study

open access: yesJPGN Reports, EarlyView.
ABSTRACT Esophageal varices (EV) need monitoring in patients with portal hypertension. In 2022, a single‐use ultra‐slim (3.5 mm) gastroscope was approved for use in children and adults. This study evaluated if an ultra‐slim gastroscope could evaluate, grade, and corroborate the presence of EV in sedated pediatric patients as compared to standard oral ...
Vishruti Patel   +6 more
wiley   +1 more source

Shaping the research agenda of pediatric gastroenterology, hepatology, and nutrition: The proposal from an Italian Society of Pediatric Gastroenterology, Hepatology and Nutrition (SIGENP) expert group

open access: yesJPGN Reports, EarlyView.
Abstract The Italian Society of Pediatric Gastroenterology, Hepatology and Nutrition (SIGENP) recognized the need to define research priorities and identify knowledge gaps to guide future investigations in pediatric digestive health. Following international examples, SIGENP aimed to provide a structured framework that aligns scientific innovation with ...
Carlo Agostoni   +46 more
wiley   +1 more source

Routine MDM2 FISH Testing and Preoperative Biopsy Reduces Recurrence Rate of Atypical Lipomatous Tumours

open access: yesJournal of Surgical Oncology, EarlyView.
ABSTRACT Background Although MDM2 FISH test has been increasingly used to differentiate ALT and benign lipomatous tumours, its impact on clinical outcome remains underexplored. This study investigated whether routine MDM2 FISH testing on preoperative biopsy is associated with a reduction in the recurrence risk of ALT.
Samuel O. H. Ching   +5 more
wiley   +1 more source

Plasma Cell Mucositis: A 20‐Year Retrospective Review at a Tertiary Center

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Background Plasma cell mucositis (PCM) is a rare, chronic inflammatory condition of mucosal surfaces that is likely underdiagnosed and underreported, with limited data on its clinical characteristics, extracavitary involvement, and treatment outcomes.
Miguel A. Aristizabal‐Torres   +4 more
wiley   +1 more source

Connecticut cost study report

open access: yes, 2006
"February 1, 2006."; "Pursuant to Public Act 05-280, Sec. 35, The Department of Mental Retardation contracted with Solutions Consulting Group, LLC of Maine for a unit cost study for the Birth-To-Three Early Intervention Program ..."--Letter of ...
Solutions Consulting Group.
core   +1 more source

Oral vascular lesions: clinical, diagnostic and therapeutic evaluations

open access: yesRevista Cubana de Estomatología, 2018
Introduction: Vascular disorders affect the head and neck regions with high incidence. When they affect the oral region, there is a predilection for lips, tongue and mouth commissure, predominantly in the female.
Marcelo Gadelha Vasconcelos   +3 more
doaj  

Sclerosing cholangitis.

open access: yes, 1995
PURPOSE OF REVIEW: Primary sclerosing cholangitis is a chronic cholestatic liver disease characterized by strictures of the biliary tree. It is immune mediated, although the precise cause remains unknown. Recent reports have shown a higher prevalence and
MacFaul, GR   +6 more
core   +1 more source

Hemithyroidectomy Eligibility Under ATA 2015 and 2025 Criteria: A Reclassification Cohort Study

open access: yesThe Laryngoscope, EarlyView.
ABSTRACT Objective To compare hemithyroidectomy eligibility and completion thyroidectomy recommendations under the ATA 2015 and ATA 2025 criteria within the same patient cohort (primary aim) and, as a secondary descriptive analysis, to assess the concordance between these guideline‐based classifications and the operations actually performed.
Muhammer Ergenç   +3 more
wiley   +1 more source

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