Results 31 to 40 of about 6,612 (262)

Effect of Hyaluronic Acid and Pluronic-F68 on the Surface Properties of Foam as a Delivery System for Polidocanol in Sclerotherapy [PDF]

, 2020
The use of foams to deliver bioactive agents and drugs is increasing in pharmaceutics. One example is the use of foam as a delivery system for polidocanol (POL) in sclerotherapy, with the addition of bioactive compounds to improve the delivery system ...
Cabrerizo Vílchez, Miguel Ángel, Castillo Santaella, Teresa del, Gálvez Ruiz, María José, Holgado Terriza, Juan Antonio, Maldonado Valderrama, Julia, Martínez González, Inmaculada, Selles Galiana, Fernando, Yang, Yan   +7 more
core   +2 more sources

Effect of Mild to Moderate Hepatic Impairment on Valemetostat Pharmacokinetics: An Open‐Label, Phase I Study

Clinical Pharmacology in Drug Development, EarlyView.
Abstract Valemetostat tosylate (valemetostat) is a dual inhibitor of enhancer of zeste homolog (EZH) 2 and EZH1, approved in Japan for the treatment of relapsed/refractory peripheral T‐cell lymphoma and adult T‐cell leukemia/lymphoma. This Phase I, open‐label study evaluated the pharmacokinetics and safety of a single 50‐mg oral dose of valemetostat in
Masaya Tachibana, Thuy Vu Craveiro, Thomas C. Marbury, Samuel Oberstein, George J. Atiee, Ben Tao, Takako Shimizu, Yvonne Lau, Malaz A. Abutarif   +8 more
wiley   +1 more source

Human Hepatobiliary Organoids: Recent Advances in Drug Toxicity Verification and Drug Screening

Biomolecules
Many drug and therapeutic modalities have emerged over the past few years. However, successful commercialization is dependent on their safety and efficacy evaluations.
Haoyu Fang, Haoying Xu, Jiong Yu, Hongcui Cao, Lanjuan Li   +4 more
doaj   +1 more source

A Proposed Therapeutic Algorithm Based on Multiple Case Analysis Regarding the Repair Options of Iatrogenic Biliary Lesions Following Open and Laparoscopic Surgery [PDF]

, 2016
Introduction: the problem of the iatrogenic lesions of the main biliary pathways is far from being completely clarified and still represents a serious surgical situation, during both open and laparoscopic surgeries.
Beliș, Vladimir, Moldovan, Cosmin Alec, Ungureanu, Dan Florin   +2 more
core   +2 more sources

Effects of sclerosing agents on head and neck hemangiomas : a systematic review [PDF]

, 2019
The aim of this study was to systematically review the literature for studies that investigated the effects of sclerosing agents on head and neck hemangiomas.
Melo, Gilberto, Modolo, Filipe, Munhoz, Etiene de Andrade, Scotti, Fernanda-Marcello, Stuepp, Rúbia-Teodoro   +4 more
core   +1 more source

The Myriad Spectrum of Salivary Gland Lesions: Cytohistological Correlation on Fine Needle Aspiration Cytology, Core Needle Biopsy, and Resections in a 5‐Year Single Institutional Experience of North India

Diagnostic Cytopathology, EarlyView.
ABSTRACT Introduction Fine needle aspiration cytology (FNAC) is a cost‐effective method used for preoperative diagnosis of salivary gland lesions. Due to the wide range of tumor types, overlapping morphology, and limited cellularity, diagnosing salivary gland lesions on FNAC can be challenging.
Zachariah Chowdhury, Pallavi Majumdar, Sumeet Narain, Komal Lamba   +3 more
wiley   +1 more source

Diagnosis of pancreaticobiliary malignancy by detection of minichromosome maintenance protein 5 in biliary brush cytology [PDF]

, 2017
Background: Biliary brush cytology is the standard method of evaluating biliary strictures, but is insensitive at detecting malignancy. In pancreaticobiliary cancer minichromosome maintenance replication proteins (MCM 2–7) are dysregulated in the ...
Chapman, MH, Huggett, MT, Johnson, GJ, Keane, MG, Mackay, J, Pereira, SP, Thorburn, D, Webster, GJ   +7 more
core   +1 more source

Gynecological surgery in patients with kidney failure on chronic kidney replacement therapy: A binational data linkage study of morbidity and mortality outcomes

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective This study evaluates postoperative outcomes of patients with kidney failure on chronic kidney replacement therapy after gynecological surgery. Methods This binational data‐linkage study identified patients with kidney failure via the Australia and New Zealand Dialysis and Transplant Registry who underwent major gynecological ...
Mina Khair, Dharmenaan Palamuthusingam, Carmel M. Hawley, Elaine M. Pascoe, Usama Shahid, David W. Johnson, Magid Fahim   +6 more
wiley   +1 more source

Gastrointestinal cancer screening and surveillance programmes : a worldwide perspective : part 2 [PDF]

, 2012
Part 1 of this article can be found through this link: https://www.um.edu.mt/library/oar//handle/123456789/12879Part 2 of this article. Cancer is a leading cause of death worldwide and such deaths are projected to continue to rise, creating ...
Gerada, Jurgen
core   +2 more sources

FIGO guideline on liver disease and pregnancy

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract The number of women entering pregnancy with chronic liver disease is rising. Gestational liver disorders affect 3% of the pregnant population. Both can be associated with significant maternal and fetal morbidity and mortality. European guidance has recently been published to inform management.
Melanie Nana, Virna Medina, Cynthia Maxwell, Ciara McCormick, Gloria Taliani, Ulrich Beuers, Deborah Money, Bo Jacobsson, Anil Kapur, Titus Beyuo, Francisco Ruiloba, Graeme Smith, Lina Bergman, Sharleen O'Reilly, Patrick O'Brien, Mark Hanson, Mary Rosser, Claudio Sosa, Sumaiya Adam, Valerie Guinto, Liona Poon, Fionnuala McAuliffe, Catherine Williamson, on behalf of the FIGO Committee on Impact of Pregnancy on Long‐term Health, FIGO Committee on Infections during Pregnancy and the FIGO Division of Maternal and Newborn Health   +24 more
wiley   +1 more source