Results 121 to 130 of about 1,097,866 (354)

Acoustic Measures Capture Speech Dysfunction in Spinocerebellar Ataxia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxias (SCA) are hereditary cerebellar degenerative disorders with a common feature of dysarthria, involving impaired phonatory and articulatory control of speech, thereby affecting social communication. In this study, we investigated whether acoustic measures could objectively measure speech dysfunction and identify
Zena Fadel, Charlotte Hennessey, Hannah Lee, Pia Parekh, Sheng‐Han Kuo, Ami Kumar   +5 more
wiley   +1 more source

Central vein sign and diffusion MRI differentiate microstructural features within white matter lesions of multiple sclerosis patients with comorbidities [PDF]

, 2023
Caterina Lapucci, Francesco Tazza, Silvia Rebella, Giacomo Boffa, Elvira Sbragia, Nicolò Bruschi, Elisabetta Mancuso, Nicola Mavilio, Alessio Signori, Luca Roccatagliata, Maria Cellerino, Simona Schiavi, Matilde Inglese   +12 more
openalex   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Successful treatment of refractory eosinophilic fasciitis with reslizumab

JAAD Case Reports, 2020
Mahta Mortezavi, MD, Mary Barrett, MD, Mohammadomid Edrissian, MD   +2 more
doaj   +1 more source

COVID-19 Vaccination Willingness and Acceptability in Multiple Sclerosis Patients: A Cross Sectional Study in Iran [PDF]

, 2022
Seyed Massood Nabavi, Mehrnoosh Mehrabani, Leila Ghalichi, Mohammad Ali Nahayati, Mehran Ghaffari, Fereshteh Ashtari, Seyed Ehsan Mohammadianinejad, Shahedeh Karimi, Leila Faghani, Sepideh Yazdanbakhsh, Abbas Najafian, Koorosh Shahpasand, Massoud Vosough   +12 more
openalex   +1 more source

Effectiveness and Safety of Nusinersen and Risdiplam in Spinal Muscular Atrophy: A Systematic Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinal Muscular Atrophy (SMA) is a rare genetic disorder marked by progressive muscle weakness and mobility loss. It has a profound physical, emotional and social impact on patients and caregivers, requiring comprehensive medical and supportive care.
Amin Mehrabian, Peter Auguste, Amy Grove, Anna Brown, Janette Parr, Mubarak Patel, Furqan Butt, Jeremiah Donoghue, Mehdi Yousefi, Jo Parsons   +9 more
wiley   +1 more source

COVID-19 and Multiple Sclerosis: A Complex Relationship Possibly Aggravated by Low Vitamin D Levels [PDF]

, 2023
William Danilo Fernandes de Souza, Denise Morais da Fonseca, Alexandrina Sartori   +2 more
openalex   +1 more source

Evaluation of the Efficacy and Safety of Satralizumab in a Pregnant NMOSD Patient With AQP4/MOG‐IgG Dual Seropositive: A Case Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Neuromyelitis Optica Spectrum Disorder (NMOSD) is a chronic autoimmune neuroinflammatory disease, typically characterized by antibodies against aquaporin 4 (AQP4‐IgG) or myelin oligodendrocyte glycoprotein (MOG‐IgG). Simultaneous seropositivity for both antibodies in a single patient is exceedingly rare.
Yeting Luo, Shuhua Xie, Xianghong Liu
wiley   +1 more source

Ferroptosis promotes T-cell activation-induced neurodegeneration in multiple sclerosis

, 2022
Jinyuan Luoqian, Wenyong Yang, Xulong Ding, Qing‐zhang Tuo, Zheng Xiang, Zhaoyue Zheng, Yujie Guo, Li Li, Pengbo Guan, Scott Ayton, Biao Dong, Huiyuan Zhang, Hongbo Hu, Peng Lei   +13 more
openalex   +2 more sources

Study protocol for an online lifestyle modification education course for people living with multiple sclerosis: the multiple sclerosis online course (MSOC) [PDF]

, 2023
Jeanette C. Reece, Maggie Yu, William Bevens, Steve Simpson, George A Jelinek, Pia Jelinek, Rebekah Davenport, Nupur Nag, Kathleen Gray, Sandra Neate   +9 more
openalex   +1 more source