Results 281 to 290 of about 1,097,866 (354)

Consensus on recommended evaluation tools in multiple sclerosis (CORE-MS): A Delphi study protocol on balance and gait assessment. [PDF]

PLoS One
Cardini R, Gervasoni E, Germanotta M, Aprile IG, Cecchi F, Pedrini C, Gobbo M, Pollet J, Pullara R, Amato MP, Pasquini G, Gerli F, Cattaneo D.   +12 more
europepmc   +1 more source

Engineered GM1 Intersects Between Mitochondrial and Synaptic Pathways to Ameliorate ALS Pathology

Advanced Science, EarlyView.
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease driven by genetic and molecular disruptions affecting energy balance, protein homeostasis, and stress responses in nerve cells. Studies using human and rodent models identified convergent defects in mitochondria and synaptic function.
Federica Pilotto, Tristan Dellazizzo Toth, Silvano Bond, Alexander Schmitz, Rim Diab, Sara Y. Ngo Tenlep, Brian Mooney, Silvia Erni, Martina Schobesberger, Olivier Scheidegger, Camille Peitsch, Smita Saxena   +11 more
wiley   +1 more source

A new modic changes classification and its impact on posterior lumbar interbody fusion. [PDF]

BMC Musculoskelet Disord
Zhang X, Qiao X, Zhou X, Wang L.
europepmc   +1 more source

PFOS Disrupts Oocyte Maturation and Early Embryonic Development via Ovarian FOXK1 O‐GlcNAcylation in Mice

Advanced Science, EarlyView.
Perfluorooctane sulfonate (PFOS) exposure disrupts oocyte maturation and early embryonic development. This study elucidates the mechanism by which enhanced O‐GlcNAcylation of FOXK1 underlies the PFOS‐induced reduction of progesterone levels in granulosa cells and the disturbance of follicular microenvironment.
Shuwen Han, Qin Yuan, Zhu Wu, Yaohui Fang, Hong Qian, Jiale Zhu, Yuchen Zhang, Ke Deng, Liangliang Su, Haibo Xu, Haotian Shu, Yiming Gong, Qiaoqiao Xu, Guizhen Du, Di Wu, Yun Fan, Chuncheng Lu   +16 more
wiley   +1 more source

Close association of kinesiophobia with physical performance in patients with systemic sclerosis. [PDF]

Rheumatol Int
Uluışık A, Turk I, Yetişir A, Sariyildiz A, Coskun Benlidayi I.   +4 more
europepmc   +1 more source

Aberrant Splicing Signatures Underpin Oligodendrocyte Damage in ALS and Neuron Loss in FTD

Advanced Science, EarlyView.
Integrating bulk and single‐nucleus RNA‐seq from ALS and FTD patients, we revealed distinct cellular dysfunctions, with severe oligodendrocyte damage in ALS and pronounced neuron loss in FTD. We identified cell‐type‐specific aberrant splicing events as potential biomarkers with robust classification performance, some of which produce de novo peptides ...
Chen Du, Yinming Li, Rong Wu, Yufei Shen, Jiayi Yang, Xuan Xiao, Yu Zhou   +6 more
wiley   +1 more source

Hyaluronidase for microstomia in fibrosing skin disease: Systematic review and case series

JAAD International
Catherine Zhu, MD, Ghassan Barnawi, MD, Elen Grigorchuk, Ethan Bendayan, Katya Peri, MSc, François Lagacé, MD, Houriah Y. Nukaly, MD, Elena Netchiporouk, MD, MSc   +7 more
doaj   +1 more source

Assessing validity and reliability of the Benefit Finding Scale in Italian people with multiple sclerosis and their caregivers. [PDF]

Neurol Sci
Giordano A, Rosato R, Biolzi B, Chisari CG, Falautano M, Grobberio M, Niccolai C, Pietrolongo E, Quartuccio ME, Viterbo RG, Fave AD, Bassi M.   +11 more
europepmc   +1 more source

Systematic Benchmarking of a Noise‐Tolerant Conductive Hydrogel Electrode for Epidermal Bioelectronics

Advanced Science, EarlyView.
General schematic of the approach. Abstract Conventional Silver/Silver Chloride (Ag/AgCl) electrodes remain the clinical standard for electrophysiological monitoring but are hindered by poor skin conformity, mechanical rigidity, and signal degradation, particularly under motion or sweat.
Nazmi Alsaafeen, Ioannis Ziogas, Shirina Alsaedi, Mouza Alshehhi, Shahd Almheiri, Adil Rehman, Khulood Al Shehhi, Hani Saleh, Ahsan Khandoker, Charalampos Pitsalidis, Antoun Khawaja, Anna‐Maria Pappa   +11 more
wiley   +1 more source

Prevalence and severity of complicated Raynaud's phenomenon in limited and diffuse systemic sclerosis: a multicenter study in Iraq. [PDF]

Reumatologia
Jaafar F, Moayad Z, Gorial F, Alkazzaz A.   +3 more
europepmc   +1 more source