Results 61 to 70 of about 188,655 (392)

Analysis of Postoperative Pain at the Anterior Iliac Crest Harvest Site: A Prospective Study of the Intraoperative Local Administration of Ropivacaine [PDF]

Asian Spine Journal, 2015
Study DesignThis was a prospective randomized comparative study.PurposeThe aim of this study was to objectify donor site-related pain following anterior iliac crest graft harvesting, in patients who have undergone multilevel anterior cervical discectomy ...
Juliane Zenner, Wolfgang Hitzl, Michael Mayer, Heiko Koller   +3 more
doaj   +1 more source

Inhibition of Hypersialylation in Human Intervertebral Disc Degeneration Modulates Inflammation and Metabolism

Advanced Science, EarlyView.
Glycosylation, specifically hypersialylation, is identified as a critical factor in human intervertebral disc (IVD) degeneration—a major cause of low back pain. This study demonstrates that inhibiting sialylation reduces inflammation and oxidative stress in IVD tissues, suggesting new therapeutic possibilities.
Kieran Joyce, Aert F. Scheper, Aung Myat Phyo, Roisin O’ Flaherty, Richard Drake, Aiden Devitt, Martina Marchetti‐Deschmann, Radka Saldova, Abhay Pandit   +8 more
wiley   +1 more source

Upregulation of microRNA-96-5p is associated with adolescent idiopathic scoliosis and low bone mass phenotype

Scientific Reports, 2022
Bone densitometry revealed low bone mass in patients with adolescent idiopathic scoliosis (AIS) and its prognostic potential to predict curve progression.
Huanxiong Chen, Kenneth Guangpu Yang, Jiajun Zhang, Ka-yee Cheuk, Evguenia Nepotchatykh, Yujia Wang, Alec Lik-hang Hung, Tsz-ping Lam, Alain Moreau, Wayne Yuk-wai Lee   +9 more
doaj   +1 more source

Acetylation Regulates ACSL4 Degradation Through Chaperone‐Mediated Autophagy to Alleviate Intervertebral Disc Degeneration

Advanced Science, EarlyView.
Intervertebral disc degeneration is triggered by ACSL4 accumulation‐mediated ferroptosis of nucleus pulposus cells due to CMA dysfunction. KAT2B promotes ACSL4 degradation via CMA through acetylation. AAV‐mediated LAMP2A delivery or engineered exosomes rescue nucleus pulposus cell senescence and disc degeneration.
Zhouwei Wu, Zhichen Jiang, Chenglong Hong, Shu Yang, Shuqing Jin, Chenyu Wu, Kaijie Guo, Jiang Liu, Shaobo Xu, Chenggui Wang, Xiangyang Wang   +10 more
wiley   +1 more source

Physiotherapy scoliosis-specific exercises – a comprehensive review of seven major schools

Scoliosis and Spinal Disorders, 2016
In recent decades, there has been a call for change among all stakeholders involved in scoliosis management. Parents of children with scoliosis have complained about the so-called “wait and see” approach that far too many doctors use when evaluating ...
Hagit Berdishevsky, V. Lebel, J. Bettany-Saltikov, M. Rigo, A. Lebel, A. Hennes, M. Romano, M. Białek, A. M’hango, T. Betts, J. D. de Mauroy, J. Durmała   +11 more
semanticscholar   +1 more source

Growth Standards for Children With Smith–Magenis Syndrome (SMS)

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Smith–Magenis syndrome (SMS, OMIM 182290) is a complex syndromic diagnosis marked by neurobehavioral differences and distinct facial dysmorphisms, caused by haploinsufficiency of the retinoic acid‐1 (RAI1) gene either by a pathogenic sequence variant or deletion at chromosome 17p11.2 involving a portion or all of this gene.
Julie Hoover‐Fong, John McGready, Leah Fleming, Kerry Schulze, Folami Duncan, Alexis Leonard, Marie Christine de Blois Boucard, Danilo Moretti‐Ferreira, Andrea L. Gropman, Wendy J. Introne, Ann C. M. Smith   +10 more
wiley   +1 more source

Polyarticular Septic Arthritis in an Immunocompetent Adult: A Case Report and Review of the Literature

Case Reports in Orthopedics, 2015
Septic arthritis is a clinical emergency requiring prompt diagnosis and treatment to avoid significant morbidity and mortality. Polyarticular septic arthritis (PASA) accounts for 15% of all infectious arthritides and rarely occurs in immunocompetent ...
Annelise Miller, Fahad Abduljabbar, Peter Jarzem   +2 more
doaj   +1 more source

Recipients of electric-powered indoor/outdoor wheelchairs provided by a National Health Service: A cross-sectional study [PDF]

, 2013
This is the post-print version of the final paper published in Archives of Physical Medicine and Rehabilitation. The published article is available from the link below.
Albright, Andrew O. Frank, Arthanat, Arva, Auger, Brandt, British Society of Rehabilitation Medicine, Burnfield, Cooper, Cooper, Davies, Dicianno, Evans, Evans, Fitzgerald, Frank, Frank, Frank, Frank, Gibson, Giesbrecht, Greer, Johnson, Karmarkar, Kenneson, Kirby, Lindsay, Lofqvist, Lord, Lorraine H. De Souza, May, Murphy, Muscular Dystrophy Campaign, Richardson, Rodby-Bousquet, Sonenblum, Vignier, Ward, Warren, Washington, West, Westgren, Wiart   +42 more
core   +1 more source

Nance‐Horan Syndrome: Further Delineation of the Affected Male and the Female Carrier Phenotypes

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Nance‐Horan syndrome (NHS; OMIM 302350) is a rare, X‐linked syndrome characterized by bilateral congenital cataracts leading to profound vision loss, specific dental anomalies including characteristic screwdriver blade‐shaped incisors, facial anomalies, and intellectual disability.
Maria K. Haanpää, Chad R. Haldeman‐Englert, Marja Hietala, Melisa S. Tanverdi, Patrick P. Koty, Diana Brightman, Eniolami Dosunmu, Shailja Tibrewal, Savleen Kaur, Anupriya Kaur, Raj Kumar Verma, Alejandra G. de Alba Campomanes, Virginia Utz, Anne M. Slavotinek, Cynthia Curry   +14 more
wiley   +1 more source

Limbus vertebrae of the cervical spine: A case report

Clinical Case Reports, 2022
Limbus vertebra is a common radiological finding in an adult, especially in the mid‐lumbar region. However it is less commonly seen in the mid cervical region.
Eleni Pappa, Ioannis Chatzikomninos
doaj   +1 more source