Results 141 to 150 of about 1,292,086 (300)

The Scope, 2010-06, Vol. 05 Num. 11, Issue 107

, 2010
The Scope, 2010-06, Vol. 05 Num.

core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Päästölaskenta teleoperaattorin arvoketjussa. Scope 3 kategoriat 1 ja 2

Greenhouse gas (GHG) emissions are the main cause of global warming. The Information and Communication Technology (ICT) sector is a significant contributor to the global GHG emissions and teleoperators are a part of the sector.
Palonen, Otto
core  

The Scope, 2011-07, Vol. 07 Num. 06, Issue 120

, 2011
The Scope, 2011-07, Vol. 07 Num.

core  

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Difference of Supply Chain GHG Emissions (Scope 1, Scope 2 and Scope 3 Emissions) Among Sectors

Journal of Life Cycle Assessment, Japan, 2015
openaire   +2 more sources

The Scope, 2010-07, Vol. 06 Num. 01, Issue 108

, 2010
The Scope, 2010-07, Vol. 06 Num.

core  

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

The Scope, 2011-10, Vol. 07 Num. 09, Issue 123

, 2011
The Scope, 2011-10, Vol. 07 Num.

core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source