Results 161 to 170 of about 1,292,086 (300)

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Beyond a solvent: HFIP as a game-changing medium in heterocyclic ring construction. [PDF]

Beilstein J Org Chem
Alakonda LM, Varala R, Seema V, Alam MM.
europepmc   +1 more source

Preoperative Carbohydrate Loading in Pediatric Surgery: A Scoping Review of Current Clinical Trials [version 3; peer review: 1 approved, 2 approved with reservations]

F1000Research
Abstract Introduction Preoperative carbohydrate loading (PCL), part of Enhanced Recovery After Surgery (ERAS) protocols, involves giving carbohydrate-rich liquids before surgery instead of traditional fasting. It improves glucose control, reduces insulin resistance, and enhances patient comfort.
Yunita Widyastuti, Amar Rayhan, Anisa Fadhila Farid, Djayanti Sari   +3 more
openaire   +1 more source

The Scope, 2009-05, Vol. 04 Num. 08, Issue 081

, 2009
The Scope, 2009-05, Vol. 04 Num.

core  

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

The Scope, 2013-02, Vol. 09 Num. 01, Issue 137

, 2013
The Scope, 2013-02, Vol. 09 Num.

core  

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Endoscopic Serosal Patch: Over-the-Scope Clip Closure of a Perforated Peptic Ulcer Using a Novel Salvage Technique. [PDF]

ACG Case Rep J
Savino C, Pezzino EC, Jain SS, Lele S, Issa N, Saffo S.   +5 more
europepmc   +1 more source

The Scope, 2010-09, Vol. 06 Num. 03, Issue 110

, 2010
The Scope, 2010-09, Vol. 06 Num.

core  

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source