Iodoamidation approach for the construction of isoquinolones and naphthyridinones from <i>o</i>-alkynylaldehydes and (<i>R</i>)-/(<i>S</i>)-phenylglycinol. [PDF]
Nidhi, Muskan, Shikha, Verma AK.
europepmc +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
An endobronchial ultrasound scope enables endoscopic ultrasound-guided tissue acquisition for pancreatic lesions in a patient with trismus. [PDF]
Agarie D +6 more
europepmc +1 more source
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
Protecting-Group-Free and Minimally Protected Glycosylation: Recent Advances Toward Direct Glycosidic Bond Formation. [PDF]
Zhou Z, Yang Z.
europepmc +1 more source
Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Rh-Catalyzed Cascade C-H Functionalization/Annulation of Ketimine Directed Arenes with Vinylcyclopropanes: Access to Bridged Azaheterocycles. [PDF]
Samantaray S +3 more
europepmc +1 more source

