Results 111 to 120 of about 1,278,781 (270)

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

HydraGuard-ID: A Hybrid Ensemble Framework With Stratified Feature Selection for High-Accuracy DDoS Attack Detection

IEEE Access
Distributed Denial-of-Service attacks continue to threaten heterogeneous IoT network infrastructure all over the world. In response to these attacks’ complexity, traditional detection methods fail to adapt to evolving threats.
L. Sankar Ganesh, P. Mohan Kumar
doaj   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Seeing the Skin Deeper: Interpretable Multi-Task Framework for Skin Lesion Diagnosis Using Superpixel Graphs

IEEE Access
Accurate and early identification of malignant skin lesions is critical for successful intervention and beneficial prognoses. Nevertheless, most current deep learning models concentrate solely on lesion classification, omitting simultaneous prediction of
J. G. Jerlshin, Abhishek Rudra Pal, Rituparna Datta, Afnan Shaik Javeed, J. S. Vittal   +4 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Multi-Class Kidney Abnormalities Detecting Novel System Through Computed Tomography

IEEE Access
Impaired renal function poses a risk across all age groups. Because of the global shortage of nephrologists, the growing public health concern over renal failure, and technological improvements, there is a demand for an AI-driven system capable of ...
Sagar Dhanraj Pande, Raghav Agarwal
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

PotatoLeafNet: two-stage convolutional neural networks for effective Potato Leaf disease identification and classification

Frontiers in Artificial Intelligence
IntroductionPotato foliar diseases, particularly early and late blight, pose a serious threat to yield and food security, yet reliable visual recognition remains challenging due to cultivar heterogeneity, variable symptom expression, and acquisition ...
Girigula Durga Bhavani, Mukkoti Maruthi Venkata Chalapathi   +1 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source