Results 211 to 220 of about 218,103 (291)
Mapping the Cerebral Organoid Landscape: A Systematic Review of Preclinical 3D Models in Neuroscience
Advanced Healthcare Materials, EarlyView.Cerebral organoids are transforming brain research, yet the field remains fragmented. This comprehensive systematic review maps 738 studies published between 2014 and 2024 to uncover trends, gaps, and opportunities across neuroscience. Introducing OrganoidMap—an interactive, open‐access platform to explore and compare models—this work enables ...Anna Wolfram, Vanessa Arnold, Maik Wolfram‐Schauerte, Anastassiya Moskalchuk, Caroline Trust, Marie Vontz, Mona Scheurenbrand, Vijayasarathy Sampath‐Kumar, Sogand Ahari, Carlos Romero‐Nieto, Lisa Sevenich +10 morewiley +1 more sourceMelt Electrowriting High Resolution Poly(ethylene‐co‐vinyl acetate) Scaffolds for Soft Tissue Engineering
Advanced Healthcare Materials, EarlyView.This work pioneers melt electrowriting (MEW) of polyethylene vinyl acetate (PEVA) to fabricate ultra‐compliant, high‐resolution scaffolds. By integrating microscale precision with soft tissue‐like biomechanics, PEVA overcomes stiffness‐driven limitations of conventional MEW polymers, establishing a mechanically biomimetic platform for soft tissue ...Finn Snow, Darcy De Rauch, Lilith Mabel Caballero Aguilar, Darcy Millett, Jasley Wilding McBride, David R Nisbet, Magdalena Kita, Elena Pirogova, Robert Michail Ivan Kapsa, Anita Quigley +9 morewiley +1 more sourceMapping Nanoscale Protein‐Corona Kinetics of DoE‐Optimized Perfluorocarbon Encapsulated‐PLGA Nanoparticles by In Situ, Time‐Resolved Synchrotron SAXS
Advanced Healthcare Materials, EarlyView.A two‐phase workflow (OFAT screening followed by central composite design) maps how processing variables tune PFCE‐PLGA nanoparticle size, dispersity, surface charge, loading, and 19F‐MRI signal. In situ, time‐resolved synchrotron SAXS tracks albumin‐corona growth on intact dispersions and reveals PFCE‐dependent adsorption pathways.Joice Maria Joseph, Maria Rosa Gigliobianco, Cristina Minnelli, Paolo Moretti, Francesco Spinozzi, Giovanna Mobbili, Sara Pistolesi, Cristina Casadidio, Gabriella Teti, Roberta Censi, Stefano Antonio Gattone, Piera Di Martino +11 morewiley +1 more sourceOxygen and ROS Delivery for Infected Wound Healing and Future Prospects
Advanced Healthcare Materials, EarlyView.Bacterial infection is a major driver of delayed wound healing and postsurgical readmissions; with rising antibiotic resistance, solid peroxide–releasing biomaterials offer sustained delivery of ROS/O2 for antimicrobial control and microenvironmental modulation.Ayden Watt, Chably Rachella, Charlotte Jaloux, Joshua Vorstenbosch, Adam Hart, Michael Tanzer, Geraldine Merle, Jake Barralet +7 morewiley +1 more sourceWound Geometry Determines Whether Aligned‐Fiber Scaffolds Accelerate or Impede Diabetic Wound Healing: A Biased Random Walk Analysis
Advanced Healthcare Materials, EarlyView.Wound closure is governed by geometry‐orientation coupling: aligned fibers speed migration along their axis but hinder perpendicular advance. In vivo diabetic wound experiments with composition‐matched fibrin, combined with an anisotropic diffusion (biased random‐walk) model, quantify this trade‐off and generate a healing landscape.Yin‐Yuan Huang, Xiangjun Peng, Yuxuan Huang, Kunkoo Kim, Chengli Li, Peilun Hu, Sean J. Wang, Rohan Avula, Chun‐Yi Yang, Pengchao Ma, Shuhui Yang, Shumeng Jiang, Guy M. Genin, Xiumei Wang +13 morewiley +1 more sourceBiomarkers for personalised prevention of chronic diseases: a common protocol for three rapid scoping reviews. [PDF]
Syst RevPlans-Beriso E, Babb-de-Villiers C, Petrova D, Barahona-López C, Diez-Echave P, Hernández OR, Fernández-Martínez NF, Turner H, García-Ovejero E, Craciun O, Fernández-Navarro P, Fernández-Larrea N, García-Esquinas E, Kuhn I, Jiménez-Planet V, Moreno V, Rodríguez-Artalejo F, Sánchez MJ, Pollan-Santamaria M, Blackburn L, Kroese M, Pérez-Gómez B. +21 moreeuropepmc +1 more sourceHow to do a systematic review [PDF]
, 2018 Alex Pollock, Banks JL, Barnett-Page E, Barnett-Page E, Bastian H, Berge E, Bobath B, Boers M, Boger EJ, Booth A, Booth A, Borah R, Brazzelli M, Cahill LS, Carr JH, Chalmers I, Chalmers I, Craig P, Davies PM, Deeks JJ, Dixon-Woods M, Eivind Berge, Fain JA, Feigin VL, Ganann R, Garner P, Glasziou P, Gotzsche PC, Gough D, Gough D, Gough D, Green BN, Greenwood N, Grimshaw J, Guyatt GH, Guyatt GH, Harden A, Higgins JPT, Hoffmann TC, Hoffmann TC, Joanna Briggs Institute, Kastner M, Katrak P, Kirkham JJ, Kreis J, Langhorne P, Lees R, Levac D, Moher D, Moher D, Moher D, Morley RF, Pendlebury ST, Peoples H, PLoS Medicine Editors, Pollock A, Pollock A, Pollock A, Pollock A, Rathbone J, Riva JJ, Rowat A, Sackett DL, Santisteban L, Saunders DH, Silagy CA, Snilstveit B, Stroke Unit Trialists Collaboration, Stroup DF, Thomas J, Tong A, Tyson SF, Tyson SF, Vickrey BG, Waddington H, Wardlaw JM, Weir MC, Whiting PF, Wildridge V, Williamson PR, Wong G, Yaffe J +81 morecore +1 more sourceControllable Dynamic Mechanical Cell Stimulation using Magnetically Actuated Artificial Cilia
Advanced Healthcare Materials, EarlyView.This paper introduces a platform based on magnetic artificial cilia for providing controllable dynamic mechanical stimulation to single cells, suitable for investigating large cell populations and enabling live cell imaging. Proof‐of‐principle experiments show that cell morphology is strongly influenced by the artificial cilia, that cellular forces can Roel Kooi, Tanveer Ul Islam, Oscar M.J.A. Stassen, Naomie Amsing, Jan de Boer, Jaap M.J. den Toonder +5 morewiley +1 more sourceA Physiological Microfluidic Blood–Brain‐Barrier Model for In Vitro Study of Nanoparticle Trafficking and Accumulation
Advanced Healthcare Materials, EarlyView.A human microfluidic blood‐brain barrier (mBBB) model enables spatially resolved comparison of nanoparticle trafficking. Extracellular vesicles (EVs), liposomes, and nanoplastics exhibit distinct transport and disruption behaviors, revealing that membrane composition and uptake pathways govern BBB interaction.Bryan B. Nguyen, Neona M. Lowe, Sophia Kellogg, Kuan‐Wei Huang, Hannah O'Toole, Elizabeth J. Hale, Venktesh S. Shirure, Bhupinder S. Shergill, Steven C. George, Randy P. Carney +9 morewiley +1 more source