Results 61 to 70 of about 30,769 (298)

Diet quality, food insecurity and risk of cardiovascular diseases among adults living with HIV/AIDS: a scoping review protocol

BMJ Open, 2021
Introduction Cardiovascular diseases (CVDs) are the single greatest contributor to global mortality. The successful introduction and scale-up of antiretroviral therapy (ART) delivered a reduction in HIV mortality.
Iyanuoluwa Oyedeji Oyetunji, Alastair Duncan, Sharmilah Booley, Janetta Harbron   +3 more
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

A Scoping Review of Exercise Interventions in Pediatric Oncology

, 2023
This will be a scoping review of the existing literature on exercise interventions in pediatric oncology patients. To date, there are no existing scoping reviews on the topic as it specifically relates to patients with B and T-cell lymphoblastic lymphoma
Mia Isabell Damaré, Dr. Claudio Battaglini, Dr. Lee Stoner, Lillian Niehaus   +3 more
core   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Dental caries in Rwanda: A scoping review

Health Science Reports, 2023
Background and Aims Dental caries is an infectious disease affecting virtually all nations, including Rwanda. In Rwanda, the burden of dental caries is an issue of public health concern.
Kehinde K. Kanmodi, Peace Uwambaye, Jimoh Amzat, Afeez A. Salami   +3 more
doaj   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Recommender systems for obesity prevention: Scoping review of reviews

SAGE Open Medicine
Introduction: Recommender systems are technology-based systems that generate recommendations or guide users to relevant information. This study is a scoping review aiming to describe what is known about the recommender systems for obesity prevention ...
Karina Karolina De Santis, Lisa Stiens, Lara Christianson, Sarah Forberger   +3 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Methods for the Clinical Validation of Digital Endpoints: Protocol for a Scoping Review Abstract

JMIR Research Protocols, 2023
BackgroundClinical trials often use digital technologies to collect data continuously outside the clinic and use the derived digital endpoints as trial endpoints.
Sílvia Rego, Ana Rita Henriques, Sofia Silvério Serra, Teresa Costa, Ana Maria Rodrigues, Francisco Nunes   +5 more
doaj   +1 more source

Topics of Study in Under-18 Padel Categories: A Scoping Review

Sports
The aim of this scoping review was to examine the existing literature on padel among young players (under 18) and classify its main research areas. A systematic search in PubMed, Scopus, and Web of Science identified 16 studies on teaching methodologies, psychological characteristics, physiological demands, physical attributes, and gameplay parameters.
Iván Martín-Miguel, Diego Muñoz, Rafael Conde-Ripoll, Álvaro Bustamante-Sánchez, Bernardino J. Sánchez-Alcaraz, Adrián Escudero-Tena   +5 more
openaire   +3 more sources