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Characterization and Exploration of Potential Neuroprotective Peptides in Walnut (Juglans regia) Protein Hydrolysate against Cholinergic System Damage and Oxidative Stress in Scopolamine-Induced Cognitive and Memory Impairment Mice and Zebrafish.

Journal of Agricultural and Food Chemistry, 2021
The purpose of this study was to determine the neuroprotective effect and mechanism of walnut protein hydrolysates (WPH) against memory deficits induced by scopolamine in mice and further to validate the potent neuroprotective peptides identified by ...
Shuguang Wang   +6 more
semanticscholar   +1 more source

Scopolamine, a toxin-induced experimental model used for research in Alzheimer's disease.

CNS and Neurological Disorders - Drug Targets, 2020
Scopolamine as a drug is often used to treat motion sickness. Derivatives of scopolamine have also found applications as antispasmodic drug among others.
Win Ning Chen, K. Y. Yeong
semanticscholar   +1 more source

Scopolamine intoxications

Intensive Care Medicine, 1983
Pure scopolamine intoxications are extremely rare. We treated a series of severe intoxications exclusively caused by scopolamine and due to the intentional mixing of pure scopolamine into drinks. The clinical course and therapy are reported. On the basis of our experience and a survey of literature, we found physostigmine to be an excellent antidote ...
L F, Lauwers   +3 more
openaire   +2 more sources

Effect of Spondias Mombin Fruit Extract on Scopolamine-induced Memory Impairment and Oxidative Stress in Mice Brain

, 2020
The effect of ethanol fruit extract of Spondias mombin (FESM) against scopolamine-induced memory impairment was evaluated in mice. Swiss mice were injected with scopolamine (3 mg kg−1, i.p) and treated with FESM (25, 100, and 400 mg kg−1) or vitamin C ...
A. Ajayi   +3 more
semanticscholar   +1 more source

Hydroxy-α-sanshool isolated from Zanthoxylum bungeanum attenuates learning and memory impairments in scopolamine-treated mice.

Food & Function, 2019
Learning and memory impairments are common symptoms of dementia in neurodegenerative disorders. Occasionally, we found that Zanthoxylum bungeanum pericarps (ZBP) significantly activated the spontaneous activity of the hippocampus (HIPP) and paraHIPP (P <
Mengmeng Zhang   +8 more
semanticscholar   +1 more source

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