Results 151 to 160 of about 2,536,246 (313)
Segregation and the Black-White Test Score Gap [PDF]
The mid-1980s witnessed breaks in two important trends related to race and schooling. School segregation, which had been declining, began a period of relative stasis. Black-white test score gaps, which had also been declining, also stagnated.
Jens Ludwig, Jacob Vigdor
core
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Determining factors influencing middle school teachers in demonstrating test score inflation
International Journal of Assessment Tools in EducationThis study examines the determinants of test score inflation among middle school teachers within Türkiye’s exam-driven education system. Test score inflation -defined as increasing students’ scores beyond actual performance due to internal or external ...
Deniz Gökçe Güngör, Ömer Kutlu
doaj +1 more source
Molecular characterization of breast cancer needle core biopsy specimens by the 21-gene Breast Recurrence Score test. [PDF]
J Surg Oncol, 2020 Jakubowski DM +9 more
europepmc +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
dearseq: a variance component score test for RNA-seq differential analysis that effectively controls the false discovery rate. [PDF]
NAR Genom Bioinform, 2020 Gauthier M +3 more
europepmc +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Statistical Method Based on Bayes-Type Empirical Score Test for Assessing Genetic Association with Multilocus Genotype Data. [PDF]
Int J Genomics, 2020 Tian Y, Ma L, Cai X, Zhu J.
europepmc +1 more source