DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang +7 more
wiley +1 more source
Sex Differences in the Neuropsychiatric Symptoms of Multiple Sclerosis: Symptômes neuropsychiatriques de la sclérose en plaques: différences selon le sexe. [PDF]
Freedman DE +3 more
europepmc +1 more source
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli +9 more
wiley +1 more source
Exploring the pathogenic mechanisms of dementia risk factors: a task-fMRI study of mild cognitive impairment. [PDF]
Shen Y +5 more
europepmc +1 more source
Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source
Can we Mitigate the Impacts of Test Anxiety Through Reappraisal Interventions? A Replication Study in Science Courses Across Multiple Institution Types in the United States. [PDF]
Thormodsæter RS +11 more
europepmc +1 more source
Assessing the resilience of portable vision tests to an uncontrolled home environment. [PDF]
Reddingius PF +3 more
europepmc +1 more source
A Machine Learning-Derived Risk Score Based on Dietary Nutrient Intake for Early Detection and Prognostic Prediction of Preserved Ratio Impaired Spirometry. [PDF]
Xie Q, Qu H, Xie S, Lan R, Li J.
europepmc +1 more source
VENOMventure, an Immersive Escape-Style Game, Teaches Families the Foundations of Phylogenetics. [PDF]
Thanukos A +3 more
europepmc +1 more source

