Genotype-Based Score Test for Association Testing in Families. [PDF]
Stat Biosci, 2015 Uh HW +3 more
europepmc +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
A Statistical Analysis of Vietnamese High School English Test Score Data
Vietnam Journal of EducationThis statistical study, perhaps the first of its kind in Vietnamese academia, has tried to understand the patterns in high school students’ pre-college national exam test scores which hold tremendous significance in students’ college or university ...
Thai Ton Duong Duong +2 more
doaj
A New Variance Component Score Test for Testing Distributed Lag Functions with Applications in Time Series Analysis. [PDF]
Stat Probab Lett, 2017 Chen YH, Mukherjee B.
europepmc +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
A score test for comparing cross-sectional survival data with a fraction of non-susceptible patients and its application in clinical immunology. [PDF]
PLoS One, 2017 Jonas SF +3 more
europepmc +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
The Weighting is the Hardest Part: On the Behavior of the Likelihood Ratio Test and the Score Test Under a Data-Driven Weighting Scheme in Sequenced Samples. [PDF]
Twin Res Hum Genet, 2017 Minică CC +7 more
europepmc +1 more source
Aerial view of the concrete tractor test track and east campus of the University of Nebraska-Lincoln looking toward the southeast.
Nebraska Tractor Test Laboratory
core
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source