Results 121 to 130 of about 182,404 (237)

Butterflies of curriculum realisation: Investigating early implementation of the Curriculum for Wales

open access: yesThe Curriculum Journal, EarlyView.
Abstract Curriculum reform provides a vital opportunity for nations to ensure learners are equipped to fully participate as citizens in the 21st century. This paper presents an understanding of educators’ response to curriculum reform, and some of its enablers and barriers.
Alison Glover   +5 more
wiley   +1 more source

Transitioning Oil and Gas Producing Regions: A Comparative Analysis of Regional Approaches in Denmark, New Zealand and Scotland

open access: yesEnvironmental Policy and Governance, EarlyView.
ABSTRACT This paper investigates how governance structures and policy approaches influence transition pathways in three major oil and gas producing regions: Esbjerg (Denmark), Taranaki (New Zealand), and Aberdeen (Scotland). The methods employ a comparative case study framework and draw on a literature review, document analysis and interviews with key ...
Sophie Kiernan, Tamara Krawchenko
wiley   +1 more source

Forecasting heart failure: Seasonal alignment of heart failure outcomes in New York

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 819-831, April 2025.
Abstract Background Seasonal variations have been observed in heart failure (HF) hospitalization. Numerous explanatory mechanisms have been proposed, but no prior studies have examined potential contributors directly. Our objective was to identify specific factors that could contribute to seasonal variability using a large longitudinal dataset of HF ...
Prerna Gupta   +5 more
wiley   +1 more source

Socio‐economic inequalities and heart failure morbidity and mortality: A systematic review and data synthesis

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 927-941, April 2025.
Abstract Socio‐economic status (SES) has been associated with incident and prevalent heart failure (HF), as well as its morbidity and mortality. However, the precise nature of the relationship between SES and HF remains unclear due to inconsistent data. This study aims to provide a comprehensive assessment and data synthesis of the relationship between
Abdul Shakoor   +8 more
wiley   +1 more source

Metabolic abnormalities and reprogramming in cats with naturally occurring hypertrophic cardiomyopathy

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1256-1270, April 2025.
Abstract Background and aims The heart is a metabolic organ rich in mitochondria. The failing heart reprograms to utilize different energy substrates, which increase its oxygen consumption. These adaptive changes contribute to increased oxidative stress.
Qinghong Li   +12 more
wiley   +1 more source

A2A Adenosine Receptor Agonists With Last‐Step Enzymatic 18F‐Labelling Potential (Fluorinase) for Positron Emission Tomography (PET)

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
This study exploits the comparable binding tolerances between the fluorinase enzyme and the A2A adenosine receptor towards the development of novel C‐2 functionalised 5′‐fluorodeoxy‐adenosine (FDA)‐based agonists with enzymatic 18F‐labelling capability for positron emission tomography (PET).
Nicolas Charalambous   +6 more
wiley   +1 more source

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