Results 201 to 210 of about 3,423,360 (305)

Multi-layer encapsulation structures for stable bottom- and top-emitting white OLED devices. [PDF]

RSC Adv
Chen PA, Yu Z, Chen H, Sheng Y, Liu C, Li X.   +5 more
europepmc   +1 more source

Gut Microbiota‐Isoallolithocholic Acid Crosstalk Promotes Calcium Oxalate Kidney Stone Formation via PARP1‐Mediated Parthanatos

Advanced Science, EarlyView.
ABSTRACT Bile acids have been implicated in calcium oxalate (CaOx) nephrolithiasis. Here, we employ multi‐omics approaches to identify isoallolithocholic acid (isoalloLCA) as the key bile acid elevated in the feces, serum, kidney, and urine of CaOx rats, confirmed by spatial metabolomics.
Zijian Zhou, Ruixi Yu, Xuan Zhou, Feng Shi, Zeyu Lin, Peng Gao, Lujia Wang, Ninghan Feng, Zhong Wu, Dawei Wang   +9 more
wiley   +1 more source

Intracellular nutrient storage during ice algal spring blooms in the Canadian high Arctic. [PDF]

iScience
Mundy CJ, Leu E, Campbell K, Galindo V, Levasseur M, Poulin M, Tremblay JÉ, Gosselin M.   +7 more
europepmc   +1 more source

One‐Step Immobilized Phage Depolymerase Coatings for Catheter‐Related Bloodstream Infections

Advanced Science, EarlyView.
Catheter‐related bloodstream infections (CRBSI) caused by drug‐resistant Gram‐negative bacteria remain a major clinical challenge. Here, a polydopamine‐assisted depolymerase coating degrades bacterial capsules and restores serum‐mediated killing, effectively suppressing biofilms and reducing bacterial burden in vitro, ex vivo, and in vivo, presenting a
Lingkai Dong, Xingjin Li, Tao Hu, Qianqian Lu, Xiaoxu Zhang, Xi Chen, Yifan Luo, Zhong Zuo, Ronald Man Yeung Wong, Miao Xu, Tiancong Zhao, Sharon Shui Yee Leung   +11 more
wiley   +1 more source

Synthesis and Performance Evaluation of a High-Temperature-Resistant Plugging and Inhibition Agent. [PDF]

Molecules
Gao Y, Ma C, Qi X, Yan H, Kamaliding N, Zhang J.   +5 more
europepmc   +1 more source

p300‐Mediated H3K18 Lactylation Drives Radiation‐Induced Pulmonary Fibrosis via VIRMA‐Dependent m6A Modification of GATA3

Advanced Science, EarlyView.
Radiation triggers glycolytic reprogramming in alveolar epithelial type II cells, causing pathological lactate accumulation. This metabolic stress drives p300‐mediated H3K18 lactylation at the VIRMA promoter, activating transcription. Elevated VIRMA enriches m6A on GATA3 mRNA, which YTHDF1 stabilizes, ultimately driving epithelial–mesenchymal ...
Junxuan Yi, Mingwei Wang, Duo Yu, Mingqi Zhao, Xinyan Wang, Shiqi Li, Xiaowen Han, Wei Wei, Shunzi Jin   +8 more
wiley   +1 more source

From Rough Lapping to Fine Lapping: A Systematic Study on Tool-Material Compatibility and Process Parameter Optimization for Polycrystalline Diamond. [PDF]

Micromachines (Basel)
Zhu Y, Chen B, Xu Y, Liao H, Li C, Chen S.   +5 more
europepmc   +1 more source

AL398, A Novel NSUN6 Inhibitor, Attenuates Epithelial‐Mesenchymal Transition and Metastasis in Endometrial Cancer by Abrogating m5C‐Dependent Stabilization of Snail mRNA

Advanced Science, EarlyView.
Proposed molecular mechanism: NSUN6 catalyzes m5C methylation on Snail mRNA to enhance its stability, leading to Snail upregulation and EMT promotion. The first‐in‐class inhibitor AL398 suppresses endometrial cancer metastasis by targeting the NSUN6‐m5C‐Snail. axis. ABSTRACT Endometrial cancer (EC) constitutes a leading gynecologic malignancy for which
Xiangzhuan Zhao, Linlin Yang, Huanxiang Chen, Chenfeng Guo, Hongshen Lu, Ying Zhu, Xuanzhi Wang, Yang Li, Ruike Zhang, Zichong Huang, Yifang Chen, Keyu Jin, Zeduo Xu, Lingxiu Meng, Longfeng Zhang, Yuanyuan Han, Yicong Yan, Qiaozhen Kang, Junhu Wan, Hongyang Liu   +19 more
wiley   +1 more source

Scaling for Scrape-Off Layer Plasma in Tokamak

Scaling for Scrape-Off Layer Plasma in Tokamak
トカマクにおけるスクレイプ・オフ層プラズマのスケーリングをDIVAをもちいて得た。このスケーリングはスクレイプ・オフ層の平均電子温度、平均密度、厚さを与える。将来の大型のトカマクでは周辺部のプラズマの温度が高くなる。また、壁からの不純物の流入はスクレイプ・オフ層で防ぐことができる。燃料は容易にスクレイプ・オフ層をとおりぬけ、主プラズマに流入することができる。
openaire   +1 more source

Arthroscopic Matrix-Associated Autologous Chondrocyte Implantation for Focal Tibial Defects. [PDF]

Arthrosc Tech
Franco D, Leite CBG, Schmidt S, Sherman N, Protzuk O, Lattermann C.   +5 more
europepmc   +1 more source