Results 101 to 110 of about 38,378 (295)

Texture profile analysis reveals a stiffer ovarian cortex after testosterone therapy : a pilot study [PDF]

, 2019
Purpose: The importance of the surrounding ovarian stromal cells and extracellular matrix in the development and maturation of follicles has recently gained attention.
De Roo, Chloë, De Sutter, Petra, Declercq, Heidi, T'Sjoen, Guy, Tilleman, Kelly, Vercruysse, Chris, Weyers, Steven   +6 more
core   +2 more sources

CORE: Cholesterol Altered Lipid Nanoparticles for Splenic Expression of mRNA Payloads

Advanced Healthcare Materials, EarlyView.
In this paper researchers introduce CORE LNPs, a new class of lipid nanoparticles engineered to redirect mRNA expression away from the liver and into the spleen, a key immune organ. By combining chemical design with computational tools, they created cholesterol analogs that enable precise spleen‐targeted expression, providing greater applications for ...
Eshan A. Narasipura, Vincent Fung, Rachel VanKeulen‐Miller, Palas B. Tiwade, Owen S. Fenton   +4 more
wiley   +1 more source

Rhinocerebral zygomycosis in Pakistan: clinical spectrum, management, and outcome [PDF]

, 2011
OBJECTIVE: To study the disease spectrum and salient management features of 36 patients with histopathologically-confirmed rhinocerebral zygomycosis seen at our academic center over a 16-year period.
Ikram, Mubasher, Iqbal, Moghira, Khan, Erum, Khan, Muhammad Aslam, Shah, Mahnaz, Smego, Raymond A., Jr   +5 more
core   +1 more source

3D Soft Hydrogels Induce Human Mesenchymal Stem Cells “Deep” Quiescence

Advanced Healthcare Materials, EarlyView.
Three‐dimensional soft hydrogels mimicking the bone marrow niche induce deep quiescence in human mesenchymal stem cells. Unlike 2D culture, 3D matrices halt proliferation, regulate cell‐cycle and quiescence markers, and downregulate mTORC1 signaling, preserving stem cell phenotype and therapeutic potential ex vivo.
David Boaventura Gomes, Timo Rademakers, Ana Filipa Henriques Lourenço, Andrea Calore, Clarissa Tomasina, Denis van Beurden, Jinjie Venema, Bryan Chömpff, Hong Liu, Nicole Bouvy, Sandra Camarero‐Espinosa, Lorenzo Moroni   +11 more
wiley   +1 more source

Hairy Leukoplakia [PDF]

, 2017
Oral hairy leukoplakia (OHL) is a disease of the mucosa first described in 1984. This pathology is associated with Epstein-Barr virus (EBV) and occurs mostly in people with HIV infection, both immunocompromised and immunocompetent, and can affect ...
Agarwala, Sanjiv S., Burgess, Jeff, Cade, James E., Lynch, Denis P, Stafford, Gary L, Vinson, Richard P.   +5 more
core   +1 more source

Epidermal Patch Technologies for Integrated Healthcare and Infection Management

Advanced Healthcare Materials, EarlyView.
Epidermal patches have evolved from simple wound coverings into multifunctional, skin‐conformable platforms integrating drug delivery, biosensing, and therapeutic functionalities. This review highlights their material innovations, fabrication strategies, and intelligent designs, including hydrogels, microneedles, and flexible electronics, while ...
Yuqi Wang, Atakan Tevlek, Pawel L. Urban, Boaz Mizrahi, Onome Ejeromedoghene, Roshan Deen, Yuanjing Lin, Jagan Mohan Dodda   +7 more
wiley   +1 more source

A case report on Traditional Chinese Medicine nursing for improving symptoms of stage 2 shoulder hand syndrome in a stroke patient based on the Collateral Disease theory and Warming-Dredging method (基于“络病理论”及“温通法”改善1例脑卒中后肩手综合征Ⅱ期患者症状的中医护理)

中西医结合护理
This article summarizes the Traditional Chinese Medicine nursing for improving symptoms of stage 2 shoulder hand syndrome in a stroke patient based on the Collateral Disease theory and Warming-Dredging method.
ZHANG Xueke (张雪珂), WEN Yan (温妍), JIANG Wei (姜薇), SONG Shuxiang (宋书香)   +3 more
doaj   +1 more source

Ubiquitin-based probes prepared by total synthesis to profile the activity of deubiquitinating enzymes [PDF]

, 2012
Epitope-tagged active-site-directed probes are widely used to visualize the activity of deubiquitinases (DUBs) in cell extracts, to investigate the specificity and potency of small-molecule DUB inhibitors, and to isolate and identify DUBs by mass ...
Berlin, I., de Jong, A., El Atmioui, D., Merkx, R., Neefjes, J.J., Ovaa, H., Robson, C.N., Rodenko, B., Wijdeven, R.H.M., Yalçin, Z.   +9 more
core   +1 more source

Fully Wireless and Flexible Valves for Multiplexed and Prolonged Intravesical Liquid Release

Advanced Healthcare Materials, EarlyView.
A fundamental mechanism for the simultaneous control of multiple magnetic valves is reported in a miniature soft robotic patch for intravesical drug delivery, enabling fully wireless and programmable liquid release. Integrated with a bioadhesive interface and induction‐coupling‐based liquid volume sensing, the soft robotic patch is promising to enable ...
Boyang Xiao, Yi Zhu, Yusheng Wang, Janene M. Pierce, Jeffrey J. Tosoian, Xiaoguang Dong   +5 more
wiley   +1 more source

Correlation between the presence of the nuclear AR-V7 androgen receptor and clinical evolution of prostate cancer: in vitro analysis of a combination of compounds targeting PI3K [PDF]

, 2019
Introduzione: PCa è una malattia multiforme e biologicamente molto eterogenea. Diversi meccanismi chiave nella progressione della malattia da androgeno-dipendente ad androgeno-indipendente (CRCP) possono essere attribuiti ad alterazione nella via di ...
Cattarino, Susanna
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