Results 61 to 70 of about 15,823,675 (338)

Transfer Learning for OCRopus Model Training on Early Printed Books

, 2017
A method is presented that significantly reduces the character error rates for OCR text obtained from OCRopus models trained on early printed books when only small amounts of diplomatic transcriptions are available.
Puppe, Frank, Reul, Christian, Springmann, Uwe, Wick, Christoph   +3 more
core   +2 more sources

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Ploughing friction and nanohardness dependent on the tip tilt in nano-scratch test for single crystal gold

, 2015
Different from macro-scale scratch, in nano-scale scratch test, the scratching tip is easily tilted, which may display a considerable change of the friction behavior.
Xiaoming Liu, 刘小明, Zhanli Liu, 魏悦广   +3 more
semanticscholar   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Features of the Influence of the Arrangement of Parts in the Chamber of Installation During Vacuum Arc Deposition on the Properties of Coatings

Applied Sciences
The effect of the spatial arrangement in the physical vapor deposition (PVD) chamber on the composition and properties of coatings is considered using the example of the deposition of the (Ti,Al)N coating.
Catherine Sotova, Marina Volosova, Alexey Vereschaka, Yuri Bublikov, Filipp Milovich, Anton Seleznev, Ilya Shmakov, Sergey Grigoriev   +7 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Post-deposition heat treatment temperature effect on hydroxyapatite coating [PDF]

MATEC Web of Conferences
This study involved the preparation of hydroxyapatite (HAP) nanoparticle coatings on a Ti6Al4V substrate using electrophoretic deposition (EPD) as the coating technique. Their surface morphology, elemental composition, microstructure, crystalline phases,
Kammoun Jassem, Dhiflaoui Hafedh, Ben Moussa Naoufel   +2 more
doaj   +1 more source

Analysis of material removal process when scratching unidirectional fibers reinforced polyester composites

Science and Engineering of Composite Materials, 2023
In this study, the micromechanical scratch behavior of unidirectional glass fiber reinforced polyester (GFRP) using several wear conditions was highlighted.
Mzali Slah, Elwasli Fatma, Zemzemi Farhat, Mezlini Salah, Mkaddem Ali, Bouazizi Mohamed Lamjed   +5 more
doaj   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source