Results 71 to 80 of about 381,300 (337)

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

Xanthan Gum as a Potential Binder for Graphite Anode in Lithium-Ion Batteries

open access: yesInternational Journal of Electrochemical Science, 2017
As an important component of the electrode, the choice of appropriate and favorable binder is significant for fabricating lithium-ion (Li-ion) batteries with good cycle stability and C-rates capacity, which are implemented for numerous applications ...
Zhaoqing Wang   +3 more
doaj   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

open access: yesFEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan   +6 more
wiley   +1 more source

Road User Detection in Videos [PDF]

open access: yes, 1963
Successive frames of a video are highly redundant, and the most popular object detection methods do not take advantage of this fact. Using multiple consecutive frames can improve detection of small objects or difficult examples and can improve speed and ...
Perreault, Hughes   +3 more
core   +3 more sources

Deep Transfer Learning: A new deep learning glitch classification method for advanced LIGO

open access: yes, 2017
The exquisite sensitivity of the advanced LIGO detectors has enabled the detection of multiple gravitational wave signals. The sophisticated design of these detectors mitigates the effect of most types of noise.
George, Daniel   +2 more
core   +2 more sources

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Study of abrasive wear rate of silicon using n-alcohols [PDF]

open access: yes
The work carried out at the University of Illinois at Chicago for the Flat-Plate Solar Array Project under contract No. 956053 is summarized. The abrasion wear rate of silicon in a number of fluid environments and the parameters that influence the ...
Danyluk, S.
core   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

The Influence of Carbon Coatings on the Functional Properties of X39Cr13 and 316LVM Steels Intended for Biomedical Applications

open access: yesMetals, 2019
Carbon coatings are used in many different industrial areas, for example in cutting, electronics, or medical applications. On the one hand, carbon coatings have improved the functional properties of medical products because of their high biotolerance ...
Roberto López   +4 more
doaj   +1 more source

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