Results 131 to 140 of about 3,711,942 (266)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Screening strategies in the presence of interactions

open access: yes, 2011
Product and process improvement can involve a large number of factors which must be varied simultaneously. Understanding how factors interact is a key step in identifying those factors that have a substantial impact on the response.
Woods, David C.   +4 more
core   +1 more source

P619: Three years of newborn screening for MPS1 in Ontario: Challenges of screening for the severe end of a disease continuum

open access: yesGenetics in Medicine Open
Melanie Lacaria   +6 more
doaj   +1 more source

Diabetic RetinaScreen Statistical Bulletin 2020-2021

open access: yes
The data in this report refers to diabetic retinopathy screening in Ireland for the years 2020 and ...
HSE National Screening Service
core  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Diabetic RetinaScreen Statistical Bulletin 2016-2017

open access: yes
The figures in this report relate to people invited by the Diabetic RetinaScreen programme for screening between 01 January 2016 and 31 December ...
HSE National Screening Service
core  

Public health screening programmes annual report : 1 April 2011 to 31 March 2012

open access: yes, 2013
This annual report presents information about the following screening programmes offered to residents across NHS Greater Glasgow and Clyde for the period 2011/12: cervical screening; bowel screening; breast screening; pregnancy screening; newborn ...
Public Health Screening Unit
core  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

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