Results 151 to 160 of about 5,243,668 (286)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

P042: California's experience with guanidinoacetate methyltransferase enzyme newborn screening on the first 100,000 samples

Genetics in Medicine Open
Kuldeep Dhillon, Jeffrey Aduviso, Jun Qiang Zhou, Long Nguyen, Alexander Cruz, Daniel Simon, Jamie Matteson, Sarah Carter, Tracey Bishop, Rajesh Sharma   +9 more
doaj   +1 more source

Sequential invitations to FOBT screening and colorectal cancer incidence. [PDF]

Sci Rep
Wang X, Ribbing Wilén H, Phillips RV, Wang Z, van der Laan MJ, Yin L, Blom J.   +6 more
europepmc   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Optimal cervical cancer screening strategies for unvaccinated and HPV-vaccinated cohorts in the United States: a comprehensive comparative modeling analysis. [PDF]

Lancet Reg Health Am
de Bondt DD, Simms KT, Naslazi E, Killen J, Kim JJ, Hontelez JAC, Burger EA, Regan MC, Smith MA, Sy S, Canfell K, de Kok IMCM.   +11 more
europepmc   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Social determinants of health screening and interventions in neonatal care pathways (NICU to follow-up): a scoping review. [PDF]

Eur J Pediatr
Nezafat Maldonado B, Evans K, Jones M, Park J, Wood E, Khan H, Cawley P.   +6 more
europepmc   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Barriers and facilitators to the utilization of cancer screening services in two Arctic Indigenous communities in Canada. [PDF]

Glob Health Action
Kolahdooz F, Jang SL, Yi KJ, Deck S, Milligan C, DeLancey D, Irlbacher-Fox S, Seaman L, Falk R, Mantla-Look L, Cook S, Corriveau A, Gotay C, Kandola K, Sharma S.   +14 more
europepmc   +1 more source

Neonatal screening [PDF]

Journal of Tropical Pediatrics, 2014
openaire   +2 more sources