Results 151 to 160 of about 3,600,121 (311)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Cost-Effectiveness of Reducing HIV Infections Through Screening and Treating Alcohol Use and Depression in KwaZulu-Natal, South Africa: A Mathematical Modeling Study. [PDF]

J Acquir Immune Defic Syndr
Jeetoo M, Yeo YR, Charles DL, Moll AP, Shenoi SV, Morojele NK, Mbaya JK, Zama P, Gasa S, Francis JM, Braithwaite RS.   +10 more
europepmc   +1 more source

BowelScreen Programme Report 2022-2023

The data in this report relates to participants invited by BowelScreen for screening from 01 January 2022 to 31 December ...
HSE National Screening Service
core  

Irish Cervical Screening Programme Report 2007

, 2009
This report outlines the programme statistics of the Irish Cervical Screening Programme in 2007 and provides an update on the establishment of CervicalCheck – The National Cervical Screening ...
Irish Cervical Screening Programme
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

P057: Reducing the false positive for guanidinoacetate methyltransferase enzyme deficiency in newborns by the addition of a second tier UPLC-MS/MS test

Genetics in Medicine Open
Jun Qiang Zhou, Kuldeep Dhillon, Jeffrey Aduviso, Long Nguyen, Alexander Cruz, Daniel Simon, Jamie Matteson, Sarah Carter, Tracey Bishop, Rajesh Sharma   +9 more
doaj   +1 more source

Adherence to follow-up cervical cancer screening and its predictors among women living with HIV in Moshi municipality, Tanzania: a hospital-based retrospective cohort study (2019-2024). [PDF]

BMJ Open
Doto D, Shirima LJ, Mmbaga B, Kinoko D, Mboya IB, Ughh IHP, Mremi A, Swai P, Mchome B.   +8 more
europepmc   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

P001: Discriminating guanidinoacetate methyltransferase enzyme deficiency false positives TPN babies by using the arginine/GUAC ratio*

Genetics in Medicine Open
Alexander Cruz, Kuldeep Dhillon, Jeffrey Aduviso, Jun Qiang Zhou, Long Nguyen, Daniel Simon, Jamie Matteson, Sarah Carter, Tracey Bishop, Rajesh Sharma   +9 more
doaj   +1 more source

Association of Oral Health Assessment Tool Findings With Periodontal Screening Outcomes in Adults With Diabetes. [PDF]

Clin Exp Dent Res
Wong G, Glastras S, Brennan S, Saponja M, Cheng A, Walk J, Cheng K, You W.   +7 more
europepmc   +1 more source