Results 161 to 170 of about 3,711,942 (266)

Opportunistic Cardiovascular Assessment During Lung Cancer Screening with Low-Dose Computed Tomography: A New Window for Prevention. [PDF]

Adv Respir Med
Sienkiewicz K, Fijałkowska J, Jelitto M, Byczkowski J, Koliński M, Szurowska E, Rzyman W.   +6 more
europepmc   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Implementation of a universal psychosocial screening program across the pediatric cancer treatment trajectory: a standard of care. [PDF]

Support Care Cancer
Barakat LP, Vargo S, Hammer SN, Reilly A, Phillips C, Burns-Lynch P, Schwartz LA, Perez MN.   +7 more
europepmc   +1 more source

Ethnicity, Immigration and Cancer Screening: Evidence for Canadian Women [PDF]

Introduction: Canada's annual immigrant intake is increasingly composed of visible minorities, with 59% of immigrants arriving in 1996-01 coming from Asia.
James Ted McDonald, Steven Kennedy
core  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Cardiac screening in the young for the detection of cardiovascular disease and prevention of sudden cardiac death. [PDF]

PLoS Med
Tardo DT, Sharma S.
europepmc   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Rebuttal to "Early Warnings About the Galleri Test Were Disregarded". [PDF]

Clin Proteomics
Klein EA, Venn O, Fung ET.
europepmc   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Mobile AI-Assisted Oral Lesion Triage for Community Oral Cancer Screening: Prospective Field Evaluation Study. [PDF]

JMIR Mhealth Uhealth
Liu HY, Huang YC, Chen SW, Wei LY, Chou CY, Lee JJ, Chen SJ, Lee CC.   +7 more
europepmc   +1 more source