Results 51 to 60 of about 2,648,798 (264)

Evaluating grant proposals: lessons from using metrics as screening device

Journal of Data and Information Science, 2023
This study examines the effects of using publication-based metrics for the initial screening in the application process for a project leader. The key questions are whether formal policy affects the allocation of funds to researchers with a better ...
Guba Katerina, Zheleznov Alexey, Chechik Elena   +2 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Implementing Risk-Stratified Breast Screening in England: An Agenda Setting Meeting

, 2022
It is now possible to accurately assess breast cancer risk at routine NHS Breast Screening Programme (NHSBSP) appointments, provide risk feedback and offer risk management strategies to women at higher risk.
Sacha J. Howell, David P. French, on behalf of the Breast Screening Risk-Stratification Agenda Setting Group on behalf of the Breast Screening Risk-Stratification Agenda Setting Group, Fiona Harrison, Anthony Howell, Katherine Payne, Lorna McWilliams, D. Gareth Evans   +7 more
core   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Standards for Quality Assurance in Cervical Screening Quality Assurance in Primary Care and Other Cervical Screening Settings

, 2020
Programme operation includes: • Coverage standard, the definition of the screening population and of the recommended screening intervals • Processes for the identification of eligible women • The acquisition and update of the demographic details of ...
Irish Cervical Screening Programme (ICSP)
core  

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

BowelScreen Programme Report 2020-2021 [PDF]

, 2023
The figures in this report relate to participants invited by BowelScreen for screening from 01 January 2020 to 31 December 2021.
HSE National Screening Service
core  

Wearable Movement Exploration Device with Machine Learning Algorithm for Screening and Tracking Diabetic Neuropathy—A Cross-Sectional, Diagnostic, Comparative Study

Biosensors
Background: Diabetic neuropathy is one of the most common complications of diabetes mellitus. The aim of this study is to evaluate the Moveo device, a novel device that uses a machine learning (ML) algorithm to detect and track diabetic neuropathy.
Goran Radunovic, Zoran Velickovic, Slavica Pavlov-Dolijanovic, Sasa Janjic, Biljana Stojic, Irena Jeftovic Velkova, Nikola Suljagic, Ivan Soldatovic   +7 more
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Cell-based high content screening using an integrated microfluidic device

, 2007
High content screening (HCS) has quickly established itself as a core technique in the early stage of drug discovery for secondary compound screening.
Qin, Jianhua, 林炳承, Shi, Weiwei, Ye, Nannan, Liu, Xin, Lin, Bingcheng, 秦建华   +6 more
core   +1 more source