Results 131 to 140 of about 9,544,902 (309)
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
The School-Years Screening Test for the Evaluation of Mental Status Test-reliability and cognitive functioning stability [PDF]
, 2003 The study investigated the test-reliability and cognitive functioning stability (argued to be separate concepts) of the School-Years Screening Test for the Evaluation of Mental Status for 5 to 8 year old children (n = 135) utilising two different models.
Spencer, Fiona H.
core
Revista Colombiana de Obstetricia y Ginecología, 2002 INTRODUCCION: En 1997 la Asociación Americana de Diabetes (ADA), recomendó cambiar los criterios de tamización y diagnóstico para la diabetes gestacional, no tamizando a las pacientes de bajo riesgo y adoptando para el diagnóstico los criterios de ...
Hernán Cortés Y +2 more
doaj
Screening tests and screening programmes
Sri Lanka Journal of Obstetrics and Gynaecology, 2012 DOI: http://dx.doi.org/10.4038/sljog.v33i4.4812 Sri Lanka Journal of Obstetrics and Gynaecology 2011; 33 : 194 ...
openaire +2 more sources
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
, 2020 Programme operation includes: • Coverage standard, the definition of the screening population and of the recommended screening intervals • Processes for the identification of eligible women • The acquisition and update of the demographic details of ...
Irish Cervical Screening Programme (ICSP)
core
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source