Results 141 to 150 of about 18,538,278 (363)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

The triple test as a screening technique for Down syndrome: reliability and relevance [PDF]

open access: yes, 2010
Tim ReynoldsClinical Chemistry Department, Queen’s Hospital, Burton-on-Trent, Staffordshire, UKAbstract: The triple test is a second trimester screening test used to identify those pregnant women who should be offered a diagnostic test to ...
Tim Reynolds
core  

Screening with young offenders with an intellectual disability [PDF]

open access: yes, 2012
The research suggests that young offenders with an intellectual disability (ID) may not always be identified within youth justice services. This pilot study assessed some aspects of the validity of a screening tool, the Child and Adolescent Intellectual ...
Curtis, Julie   +5 more
core   +1 more source

Utilidad de la prueba de tinta china como tamizaje para meningitis por Cryptococcus spp

open access: yesCiencia UNEMI, 2016
Meningitis by Cryptococcus spp is a serious public health problem in HIV + patients, therefore the Indian ink utility as screening test for this infection was determined. Cerebrospinal fluid data of 252 HIV + patients admitted from May to October 2014 at
Barcia-Castilla, Valeria   +1 more
doaj  

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

HLA-B*5701 screening for hypersensitivity to Abacavir [PDF]

open access: yes, 2008
Background Hypersensitivity reaction to abacavir is strongly associated with the presence of the HLA-B*5701 allele. This study was designed to establish the effectiveness of prospective HLA-B*5701 screening to prevent the hypersensitivity reaction to ...
Jagel-Guedes, E.   +17 more
core   +1 more source

EFFECTS OF EXCESS Cu ON GROWTH AND PHOTOSYNTHESIS OF BARLEY PLANTS. IMPLICATION WITH A SCREENING TEST FOR Cu TOLERANCE [PDF]

open access: yesJournal of Central European Agriculture, 2003
Twenty-day-old barley (Hordeum vulgare L. cv. Ribeka) plants grown as sand culture were exposed to Cu treatment (0, 10, 15 and 20 mg Cu kg-1 sand) for ten days.
A VASSILEV   +4 more
doaj  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Exploring the acceptability of two self-sampling devices for human papillomavirus testing in the cervical screening context: a qualitative study of Muslim women in London [PDF]

open access: yes, 2009
Objectives We explored Muslim women's attitudes to self-sampling for human papillomavirus (HPV) in the context of cervical cancer screening and their responses to two self-sampling devices.Setting A Muslim community centre in north-east London.Methods ...
Cadman, L   +3 more
core  

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

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