Results 51 to 60 of about 31,251 (207)

Diagnostic evaluation of IgM ELISA and IgM Immunofluorescence assay for the diagnosis of Acute Scrub Typhus in central Nepal

, 2020
BACKGROUND: Scrub typhus is an acute febrile illness caused by the obligate intracellular bacterium, Orientia tsutsugamushi. Immunochromatography (ICT) and IgM ELISA are two of the routinely employed antibody based assays for diagnosis of Scrub typhus ...
Parajuli, Keshab, Sherchand, Jeevan Bahadur, Stenos, John, Gautam, Rajendra, Tshokey, Tshokey   +4 more
core   +1 more source

Mark of scrub typhus

BMJ Case Reports, 2010
A 23-year-old previously healthy male soldier presented with intermittent fever, generalised skin rashes, and a history of right earache for 11 days. He had recently performed military training on grass before his presentation. Initially, otitis media was diagnosed, but his earache did not improve after antibiotic treatment (amoxicillin/clavulanate ...
Bor-Jen, Lee, Yau-Lin, Wang, Che-An, Tsai   +2 more
openaire   +3 more sources

Monocyte inflammation and adaptive immune dysfunction in severe Klebsiella pneumoniae pneumonia

iMeta, EarlyView.
Severe Klebsiella pneumoniae pneumonia combines intense inflammation with failure to control infection, yet the cellular basis is unclear. Using a severity‐focused single‐cell atlas of 708,894 peripheral blood mononuclear cells from 100 individuals, complemented by plasma protein measurements and flow cytometry, we show that disease severity redirects ...
Hongquan Chen, Xiaoling Wang, Xiang Liu, Kui Dong, Yanying Feng, Min Yuan, Shiyi Wang, Fangfang Fan, Yong Tian, Zhiming Kang, Xiushuai Du, Chaolu Hasi, Hong Lu, Wei Guan, Xu Chen, Mengyu Cheng, Wei Wei, Nan Guo, Zhiguo Liu, Xiaotong Qiu, Yiwei Shi, Kun Xiao, Yi Wang, Zhenjun Li   +23 more
wiley   +1 more source

Scrub Typhus Meningoencephalitis With Concurrent Brucellosis in Rural Nepal: Diagnostic Challenges With Negative PCR in a Low‐Resource Setting

Clinical Case Reports, Volume 14, Issue 10, October 2026.
Scrub typhus meningoencephalitis with concurrent Brucellosis. ABSTRACT Scrub typhus is an important cause of acute febrile illness in Nepal and can rarely present with meningoencephalitis and multiorgan involvement. We report a 32‐year‐old female farmer from rural Nepal who presented during the monsoon season with high‐grade fever, myalgia, vomiting ...
Pashupati Pokharel, Diwash Rai, Milan Bajracharya, Abhikshya Basnet, Bimal Sharma Chalise, Arati Baskota, Andrew B. Trotter   +6 more
wiley   +1 more source

A potential tool for predicting epidemic trends and outbreaks of scrub typhus based on Internet search big data analysis in Yunnan Province, China

Frontiers in Public Health, 2022
IntroductionScrub typhus, caused by Orientia tsutsugamushi, is a neglected tropical disease. The southern part of China is considered an important epidemic and conserved area of scrub typhus.
Zixu Wang, Zixu Wang, Wenyi Zhang, Nianhong Lu, Nianhong Lu, Ruichen Lv, Ruichen Lv, Junhu Wang, Junhu Wang, Changqiang Zhu, Changqiang Zhu, Lele Ai, Lele Ai, Yingqing Mao, Yingqing Mao, Weilong Tan, Weilong Tan, Yong Qi, Yong Qi   +18 more
doaj   +1 more source

Age‐Related and Seasonal Variation in Malaria and Other Causes of Fever and Their Association With Clinical Outcomes in Southern Angola: A Hospital‐Based Study

Tropical Medicine &International Health, Volume 31, Issue 9, Page 1273-1283, September 2026.
ABSTRACT Background Acute febrile illnesses in sub‐Saharan Africa are often attributed to malaria, yet many patients test negative for malaria parasites. The aetiology of nonmalarial fevers remains understudied. Here, we examine likely causes of febrile illnesses and their association with poor clinical outcomes in Angola.
Helga E. M. Gonçalves, Maria Lina Antunes, Jorge Seixas, Marcelo U. Ferreira   +3 more
wiley   +1 more source

Meteorological factors and normalized difference vegetation index drivers of scrub typhus incidence in Shandong Province based on a 16-year time-frequency analysis

BMC Public Health
Objective Scrub typhus, a natural epidemic disease that seriously impacts the health of the population, has imposed a substantial disease burden in Shandong Province.
Zhisong Ni, Shufen Li, Rui Xi, Kemeng Liang, Sihao Song, Chuanlong Cheng, Hui Zuo, Liang Lu, Xiujun Li   +8 more
doaj   +1 more source

Acute Febrile Illness With Triple Co‐Infection: A Case Report on the Diagnostic Challenges of Overlapping Febrile Illnesses

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT A 35‐year‐old female presented with 5 days of fever, fatigue, and myalgia during the post‐monsoon season at Damak Hospital, Jhapa, Nepal. Clinical examination revealed fever (102.7°F), tachycardia (110 bpm), and crackles in the right lower lung field.
Santosh Basyal, Rahul Parajuli, Dipendra Prasad Yadav, Shardul Bhattarai, Kritick Bhandari, Shrijana Basyal, Gul Zaman, Rohit Parajuli   +7 more
wiley   +1 more source

Rapid increase in scrub typhus incidence in Mainland China, 2006-2014 [PDF]

, 2016
Scrub typhus is a vector-borne disease, which has recently reemerged in China. In this study, we describe the distribution and incidence of scrub typhus cases in China from 2006 to 2014 and quantify differences in scrub typhus cases with respect to sex ...
Hu, Wen-Biao, Zhang, Wen-Yi, Liu, Yun-Xi, Magalhaes, Ricardo J. Soares, Sun, Yan-Song, Qian, Quan, Li, Shen-Long, Wu, Yi-Cheng, Soares Magalhaes, Ricardo J., Haque, Ubydul, Han, Zhi-Hai, Weppelmann, Thomas A.   +11 more
core   +1 more source

Immuno‐Informatics Design of Multi‐Epitope Vaccine Candidate Against Anaplasma phagocytophilum Using Major Surface Protein 4 (MSP‐4) Antigen

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims Bovine anaplasmosis is an intracellular tick‐borne, non‐contagious disease caused by gram‐negative bacteria of the family Anaplasmataceae and order Rickettsia. Anaplasma phagocytophilum is the etiological agent for human granulocytic anaplasmosis associated with severe health implications in parts of Europe and the USA and ...
Samson Anjikwi Malgwi, Sinalo Mani, Iliya Dauda Kwoji, Victoria T. Adeleke, Matthew A. Adeleke, Moses Okpeku   +5 more
wiley   +1 more source