Siniperca chuatsi Rhabdovirus (SCRV)-Induced Key Pathways and Major Antiviral Genes in Fish Cells [PDF]
Microorganisms, 2022 Fish rhabdoviruses, including Siniperca chuatsi rhabdovirus (SCRV), are epidemic pathogens that harm fish aquaculture. To clarify the interactions between SCRV and its host and explore antiviral targets, the present study performed transcriptome analysis
Fei Ke, Xian-Yu Meng, Qi-Ya Zhang
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Role of asparagine biosynthesis pathway in Siniperca chuatsi rhabdovirus proliferation [PDF]
Frontiers in Microbiology, 2023 Viruses are non-living organisms that rely on host cellular metabolism to complete their life cycle. Siniperca chuatsi rhabdovirus (SCRV) has caused huge economic losses to the Chinese perch (Siniperca chuatsi) industry worldwide.
Xiaozhe Fu, Yinjie Niu, Ningqiu Li
exaly +4 more sources
A Novel Protein NLRP12‐119aa that Prevents Rhabdovirus Replication by Disrupting the RNP Complex Formation [PDF]
Advanced ScienceThe accurate assembly of the ribonucleoprotein (RNP) complex is fundamental for the replication and transcription of rhabdoviruses, which are known for their broad pathogenic impact.
Weiwei Zheng +5 more
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Mandarin Fish (Siniperca chuatsi) p53 Regulates Glutaminolysis Induced by Virus via the p53/miR145-5p/c-Myc Pathway in Chinese Perch Brain Cells [PDF]
Microbiology Spectrum, 2022 p53, as an important tumor suppressor protein, has recently been implicated in host antiviral defense. The present study found that the expression of mandarin fish (Siniperca chuatsi) p53 (Sc-p53) was negatively associated with infectious spleen and ...
Ningqiu Li, Yinjie Niu, Xiaozhe Fu
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scTRIM44 Positively Regulated Siniperca Chuatsi Rhabdovirus Through RIG-I- and MDA5-Mediated Interferon Signaling [PDF]
VirusesTripartite Motif-Containing 44 (TRIM44) is responsible for cancers, neurodegenerative diseases, and viral infections. However, the role of Siniperca chuatsi TRIM44 (scTRIM44) during viral infection remains unclear.
Baofu Ma, Xiaozhe Fu, Ningqiu Li
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Aquaculture ReportsThe regulatory functions of microRNAs (miRNAs) in modulating viral pathogenesis have emerged as a pivotal research focus. Aquatic species, inhabiting ecologically distinct environments, exhibit heightened vulnerability to pathogenic challenges, posing ...
Yuanhuan Kang, Yunhang Gao
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circMORC3-encoded novel protein negatively regulates antiviral immunity through synergizing with host gene MORC3. [PDF]
PLoS Pathogens, 2023 The protein-coding ability of circRNAs has recently been a hot topic, but the role of protein-coding circRNAs in antiviral innate immunity of teleost fish has rarely been reported.
Linchao Wang +4 more
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Eukaryotic translation elongation factor 1 alpha (eEF1A) inhibits Siniperca chuatsi rhabdovirus (SCRV) infection through two distinct mechanisms. [PDF]
J Virol, 2023 ABSTRACT Rhabdoviruses are single-stranded, negative-sense RNA viruses with broad host range, several of which are important pathogens. Compared with the rhabdoviruses infecting mammals, host factors involved in aquatic rhabdovirus infection have remained largely unknown.
Meng X-Y +4 more
europepmc +3 more sources
Oxygen-Sensing Protein Cysteamine Dioxygenase from Mandarin Fish Involved in the Arg/N-Degron Pathway and Siniperca chuatsi Rhabdovirus Infection [PDF]
Viruses, 2023 Mammalia cysteamine (2-aminoethanethiol) dioxygenase (ADO) controls the stability of the regulator of G protein signaling 4 (RGS4) through the Cys branch of the Arg/N-degron pathway, thereby affecting the response of the body to hypoxia.
Wenhui Liu +5 more
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Siniperca chuatsi rhabdovirus (SCRV) induces autophagy via PI3K/Akt-mTOR pathway in CPB cells
Fish and Shellfish Immunology, 2020 Autophagy is an important mechanism for organisms to eliminate viruses and other intracellular pathogens. Siniperca chuatsi rhabdovirus (SCRV) is an agent that has caused devastating losses in Chinese perch (Siniperca chuatsi) industry. But the role of autophagy in Siniperca chuatsi rhabdovirus (SCRV) infection is not clearly understood. In this study,
Xiaozhe Fu, Chen Li, Yinjie Niu
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