Results 251 to 260 of about 14,805,720 (306)

A Biweekly GLP‐1R Agonist Designed With Drug‐Free Intervals for Enhanced Efficacy, Receptor Homeostasis and Gastrointestinal Tolerability

Diabetes, Obesity and Metabolism, Volume 28, Issue 12, Page 11143-11177, December 2026.
ABSTRACT Aim To develop a next‐generation, longer‐acting, more‐clinical‐benefits agonist to achieve sustained efficacy with improved tolerability. Methods CT130 was designed from semaglutide. Binding affinity was validated via molecular dynamics and cellular assays.
Wei Ding, Qing Liu, Qiong Luo, Xiaojun Yao, Xingxing Fan   +4 more
wiley   +1 more source

Design storm estimation for flood risk assessment in the temperate Himalayan basin using hydrological modelling. [PDF]

Sci Rep
Attar MI, Khan JN, Altaf Y, Alsubih M, Naseer S, Kumar R, Bhat OA, Bangroo SA, Sharma MK.   +8 more
europepmc   +1 more source

When People Meet Floods: Time‐Varying Population Exposure to Urban Pluvial Flooding in Rome, Italy

Journal of Flood Risk Management, Volume 19, Issue 4, December 2026.
This study introduces a time‐varying urban flood risk framework that accounts for daily mobility and scheduled events. By capturing spatiotemporal shifts in exposure, the approach generates actionable, time‐explicit insights, enabling Civil Protection to transition from static baselines to dynamic, location‐ and time‐specific emergency response ...
Edna Jessica Wilches Kochinski, Sabrina Lanciotti, Benedetta Moccia, Elena Ridolfi, Fabio Russo, Francesco Napolitano   +5 more
wiley   +1 more source

Decoding the Elusive Redox Properties of [FeS] Clusters in [FeFe]-Hydrogenase on a Nanostructured Electrode. [PDF]

J Am Chem Soc
Gao Y, Wan L, DeBeer S, Zhang L, Rüdiger O.   +4 more
europepmc   +1 more source

Tailoring Liquid Crystalline Self‐Assembly and Photophysical Properties of Unsymmetrical Fluorenones via Polar Terminal Groups

Chemistry – A European Journal, Volume 32, Issue 41, 3 November 2026.
Novel liquid crystalline fluorenones bearing various head groups were synthesized and characterized. By alteration of the head group, N, SmC, or SmA phases were obtained, and emission properties could be tuned depending on solvent or temperature. ABSTRACT In this work, a series of novel unsymmetrical fluorenone derivatives bearing various head groups ...
Falk Feucht, Franziska Müller, Johanna Osterbrink, Anna Zens, Yann Molard, Sabine Laschat   +5 more
wiley   +1 more source

Spinal cord stimulation to manage autonomic dysfunction after spinal cord injury: a systematic review. [PDF]

Front Hum Neurosci
Upadhyay P, Tsikopoulos I, Hiscock C, Houliston H, Doherty S, Knight S, Baxter D, Duffell L.   +7 more
europepmc   +1 more source

Assessing the multifunctionality of service crops in mediterranean vineyards using a functional trait approach. [PDF]

PLoS One
Garcia L, Metay A, Damour G.
europepmc   +1 more source

Domain-Adaptive Diagnosis of Lewy Body Disease with Transferability Aware Transformer. [PDF]

Med Image Comput Comput Assist Interv
Yu X, Zhang J, Cao C, Chen T, Zhuang Y, Chen M, Lyu Y, Zhang L, Su L, Liu T, Zhu D.   +10 more
europepmc   +1 more source

The Role of Iron-Hyponitrite Intermediates in Biology and Insights From Synthetic Model Complexes. [PDF]

Chemistry
Lengel MO, Lehnert N.
europepmc   +1 more source

The circular RNA circNFIX regulates MEF2C expression in muscle satellite cells in spastic cerebral palsy. [PDF]

J Biol Chem
Romero B, Hoque P, Robinson KG, Lee SK, Sinha T, Panda A, Shrader MW, Parashar V, Akins RE, Batish M.   +9 more
europepmc   +1 more source