Results 191 to 200 of about 3,843,987 (249)

Horse Head Sculpture, 12151 Avenue of the Chiefs, Custer SD, Custer County

2 x 2 b/w negative, a sculptured horse's headOrigin: Publicity Divison SD Dept. of Highways PierreCrazy Horse.
SD Department of Highways
core  

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Comparison of microdrop administration using a bottle adapter of 2.5% phenylephrine and 0.8% tropicamide with standard drop for ROP examination: a randomized controlled noninferiority trial. [PDF]

Matern Health Neonatol Perinatol
Elango V, E N, N M.
europepmc   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Healthcare resource utilization and cost of invasive pneumococcal disease, pneumonia, and acute otitis media in commercially and medicaid-insured children by risk group in the United States, 2018 to 2023. [PDF]

Pneumonia (Nathan)
Mohanty S, Done N, Song Y, Wang T, Zion A, Reichert E, Li T, White M, Cassell K, Huang YL, Johnson KD, Banniettis N, Weaver JP, Feemster KA.   +13 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

P663: A clinical laboratory’s approach to curating unexpected variants in pharmacogenes

Genetics in Medicine Open
Katie Klingaman, Mariska Davids, Hannah Wollenzien, Rachel Starks, Amelia Mroch, April Schultz, Jordan Baye, Joel Van Heukelom, Amanda Massman, Blake Atwood, Dmitry Lyalin, Sherin Shaaban, Debbie Figueroa   +12 more
doaj   +1 more source

Automated Renal Tumor Segmentation in Computed Tomography Images Using a Global Attention-Based DeepLabV3+ Model: Algorithm Development and Validation. [PDF]

JMIR Med Inform
Zhao Y, Liu J, Shao L, Li L, Liu Z, Liu Y, Wen J, Hao X, Li S, Zhao J, Song B.   +10 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Comparison of depressive symptoms and anxious distress between major depressive disorder and bipolar disorder using the CUDOS-A. [PDF]

PCN Rep
Oishi K, Matsumoto Y, Aoki Y, Takaesu Y, Murao M, Maruki T, Tsuboi T, Nakano M, Watanabe K, Sakurai H.   +9 more
europepmc   +1 more source