Results 211 to 220 of about 6,639,635 (250)

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

187 Anticoagulation Stewardship Program Impact on Deprescribing Inappropriate Antiplatelet Therapy for Patients on Oral Anticoagulation Therapy in the Outpatient Setting

Research and Practice in Thrombosis and Haemostasis
Josey Poppens, Thaddaus Hellwig, Shannon Wegleitner, Sara Zochert, Amanda Owen, Michael Gulseth   +5 more
doaj   +1 more source

circ-FSCN1 affects ferroptosis and cell viability in NSCLC via the miR-506-3p/SLC7A1 pathway. [PDF]

Transl Oncol
Yu W, Liu J, Jin M, Huang G, Huang Q.
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Effect of Intraoperative Epidural Steroid in Early Outcomes After Full-Endoscopic Lumbar Discectomy - A Randomized Controlled Trial. [PDF]

Global Spine J
Valente Aguiar P, Sousa O, Cunha M, Pereira P, Santos Silva P.   +4 more
europepmc   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Correction: Simple diameters, accurate stages:a practical approach to HD-ISS staging. [PDF]

J Neurol
Heim B, Krismer F, Hemicker G, Cerejo C, Schwarzova K, Labrecque S, Carbone F, Peball M, Scherfler C, Mahlknecht P, Grams AE, Gizewski ER, Djamshidian A, Seppi K.   +13 more
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Personalized Smartphone Messaging for Secondary Prevention After Percutaneous Coronary Intervention: Randomized Controlled Trial. [PDF]

J Med Internet Res
Lee S, Kim JB, Shin SE, Ahn J, Jeong HG, Jung KH, Song Y, Kim EJ.   +7 more
europepmc   +1 more source