Results 51 to 60 of about 2,856,652 (241)

?????????????????????????????? Sd-???????????? ???????????????????????? ?? ???????????????????????????? ???????????????? ?????? ?????????? ???????????? ????????????

open access: yes, 2021
Sd-locus, conferring resistance to rosy leaf-curling aphid, was detected in the collection of 132 apple accessions. Sd-locus was identified in genomes of 31 apple cultivars and hybrids of breeding performed Belarus, Russian, Ukraine, Germany, etc. The molecular marker technology was used for developing promising apple hybrid seedling resistant to rosy ...
openaire   +3 more sources

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa   +3 more
wiley   +1 more source

Determining of Criteria Weights Used in Evaluation of Environmental Performance Index by Objective Methods: The Case of OECD Countries

open access: yesİstanbul Gelişim Üniversitesi Sosyal Bilimler Dergisi
In recent years, social pressure on the measures taken or to be taken on the environment has been increasing, especially in developed and developing countries.
Nuh Keleş
doaj   +1 more source

'n Struktureel-historiese eksegese van Habakuk 1:2-2:4

open access: yesActa Theologica, 1996
In this article Hab 1:2-2:4 is subjected to a structural-historical exegesis. This means that both the text intern aspects (demarcation of the pericope, text critical matters and a structural analysis) and the text extern aspects (Gattung, Sitz im Leben,
SD Snyman
doaj   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Divine and human violence and destruction in Jeremiah 20:7-13

open access: yesActa Theologica, 1999
Jeremiah 20:7-13 is a text presenting the interpreter with a multitude of problems. Five main areas of research are briefly highlighted. This paper focuses on the interpretation of hamas wasod in Jer 20:8.
SD Snyman
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Utilization of the Transtheoretical Model to Determine the Qualitative Impact of a Tribal FASD Prevention Program

open access: yesSAGE Open, 2019
Alcohol consumption during pregnancy can lead to damaging effects on an infant’s health, including fetal alcohol spectrum disorders. Project Changing High-risk alcOhol use and Increasing Contraception Effectiveness Study (CHOICES), a program developed to
Olivia Lowrey   +3 more
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

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