Results 51 to 60 of about 87,234 (285)

A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1)

open access: yesJournal of Experimental Medicine, 1996
Chemotactic factors are postulated to direct emigration of lymphocytes from the blood stream into sites of inflammation. Members of a family of chemotactic cytokines, termed chemokines, have been shown to attract lymphocytes but efficacy, i.e., the ...
C. Bleul   +4 more
semanticscholar   +1 more source

SDF-1α-PPADT nanoparticles direct BMSC chemotaxis and homing in rats.

open access: yes, 2018
All rats received continuous shock for 6 s and were divided randomly into three equal groups of six. Tail vein injections were performed once a day: (A) 5 × 106 GFP-BMSCs; (B) 5 × 106 GFP-BMSCs + 18 μg/kg SDF-1α; and (C) 5 × 106 GFP-BMSCs + 1 mg/kg SDF ...
Guo-Sheng Wu (477657)   +11 more
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Dentin tubule occlusion by a 38% silver diamine fluoride gel: an in vitro investigation

open access: yesBDJ Open, 2022
Objective Silver diamine fluoride (SDF) is effective in treatment of dentin hypersensitivity and caries lesions. However, the non-viscous solution does not easily allow clinicians to control the application area.
Andreas Kiesow   +4 more
doaj   +1 more source

A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development

open access: yesJournal of Experimental Medicine, 2006
The chemokine stromal cell–derived factor (SDF-1; also known as chemokine ligand 12 [CXCL12]) regulates many essential biological processes, including cardiac and neuronal development, stem cell motility, neovascularization, angiogenesis, apoptosis, and ...
J. Burns   +14 more
semanticscholar   +1 more source

Demineralized Bone Matrix Scaffolds Modified by CBD-SDF-1α Promote Bone Regeneration via Recruiting Endogenous Stem Cells

open access: yes, 2016
The reconstruction of bone usually depends on substitute transplantation, which has drawbacks including the limited bone substitutes available, comorbidity, immune rejection, and limited endogenous bone regeneration. Here, we constructed a functionalized
Xiaoran Li (656489)   +8 more
core   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

SDF-1α-PPADT nanoparticles promote the repair of electrical burn vascular injury in rats.

open access: yes, 2018
(A) Hematoxylin and eosin staining of muscle and vascular tissues. Vascular morphology of the 6 s electrical burn group injected with SDF-1α-PPADT nanoparticles is relatively intact. Endothelial cells are better organized and continuous (arrow).
Guo-Sheng Wu (477657)   +11 more
core   +1 more source

SDF-1α/CXCR4 Signaling in Lipid Rafts Induces Platelet Aggregation via PI3 Kinase-Dependent Akt Phosphorylation. [PDF]

open access: yes, 2017
Stromal cell-derived factor-1α (SDF-1α)-induced platelet aggregation is mediated through its G protein-coupled receptor CXCR4 and phosphatidylinositol 3 kinase (PI3K).
Morio Arai   +21 more
core   +1 more source

Phase Diagrams and Piezoelectric Properties of Wurtzite Al1−x−yScxGdyN Heterostructural Alloys

open access: yesAdvanced Science, EarlyView.
This study demonstrates ferroelectricity and piezoelectric properties improvement of quaternary wurtzite Al1−x−yScxGdyN${\rm Al}_{1-x-y}{\rm Sc}_x{\rm Gd}_y{\rm N}$ films, guided by density functional theory calculations. Wurtzite Al1−x−yScxGdyN${\rm Al}_{1-x-y}{\rm Sc}_x{\rm Gd}_y{\rm N}$ films have a high optical bandgap, enhanced piezoelectric ...
Julia L. Martin   +11 more
wiley   +1 more source

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