Results 81 to 90 of about 4,922,643 (264)
, 1997 Like other cytokines, granulocyte colony-stimulating factor (G-CSF) activates a complex array of signal transduction pathways involving multiple kinases and phosphatases. We sought to identify phosphoproteins specific to G-CSF signaling.
XF Csar (14471895) +4 more
core
SDS-PAGE electrophoresis and Western blot.
, 2019 Recombinant proteins were subjected to 12% SDS-PAGE electrophoresis and stained with Coomassie Blue (A). MW: Molecular weight standard (kDa), F1, F2, F3, F4, PmMSP119 and GST; Western blot showing the recognition of proteins by a pool of sera from P ...
Wesley L. Fotoran (191095) +8 more
core +1 more source
SDS-PAGE analysis of the purified G9E Fabs.
, 2023 G9E WT and paratope mutant Fabs were expressed in Expi293 mammalian cells and purified by Ni-NTA resin. Coomassie-stained SDS-PAGE run under reduced and non-reduced condition show the band corresponding to intact Fab and reduced Fab fragments. (TIF)
Sean A. Diehl (8612892) +13 more
core +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
SDS-PAGE of Vigna unguiculata protein extract.
, 2019 The separation gel used was at 10%. M—Prestained Broad Range molecular weight marker SDS-PAGE standard BIO-RAD® (5 μL), Lane 1: Vigna unguiculata protein extract in non-reducing condition.
Graziele Cristina Ferreira (7485887) +5 more
core +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
TạO DòNG LúA THƠM KHáNG RầY NÂU, Có NăNG SUấT CAO Và PHẩM CHấT TốT
Tạp chí Khoa học Đại học Cần Thơ, 2010 Trong tình hình hiện nay, nhu cầu về các giống lúa kháng rầy nâu mới, ngắn ngày, năng suất cao và có phẩm chất tốt phục vụ cho sản xuất lúa ở Đồng bằng sông Cửu Long cũng như đáp ứng nhu cầu xuất khẩu là rất bức thiết. Một tổ hợp lai (BN x TP5) giữa dòng
Hạnh Nguyễn Thị Mai +1 more
doaj
SDS-PAGE analysis of purified recombinant cholesterol oxidase.
, 2019 The quality of the eluted pure recombinant ChO was analyzed using SDS-PAGE 10%. Lane 1: Protein marker; Lanes 2–9: Fractionated samples eluted from Ni-CAM column by 150 mM imidazole.
Mostafa Lakzaei (6331334) +4 more
core +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source