Results 121 to 130 of about 25,164,155 (279)

Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy

Ibrain, Volume 11, Issue 1, Page 44-58, Spring 2025.
In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley   +1 more source

Efficacy and Safety Profile of a Rituximab, Methotrexate, and Thiotepa‐Based Regimen in Newly Diagnosed Primary CNS Lymphoma

International Journal of Cancer, EarlyView.
Primary central nervous system diffuse large B‐cell lymphoma (PCNS‐DLBCL) lacks an optimal first‐line induction strategy, particularly for older patients and those ineligible for intensive consolidation. In this retrospective cohort of 36 newly diagnosed patients, the rituximab + methotrexate + thiotepa (RMT) regimen as first‐line induction achieved ...
Haotian Wang, Jia Li, Luming Cao, Ying Zhang, Xin Wan, Xingtong Wang, Yangzhi Zhao, Zhaoxia Li, Chengqian Chen, Yang Song, Ou Bai   +10 more
wiley   +1 more source

ESG Performance and Credit Risk: Evidence From Chinese Manufacturing Companies

International Journal of Finance &Economics, EarlyView.
ABSTRACT This study investigates the effect of corporate environmental, social, and governance (ESG) performance on credit risk using a sample of manufacturing firms listed on China's Shanghai and Shenzhen A‐share markets from 2009 to 2021. Employing fixed effects, the generalised method of moments, and instrumental variable models, we find that ...
Yanan Wang, Xiao Zhang, Michal Wojewodzki, Yuxin Jian, Fadey AbiDaoud   +4 more
wiley   +1 more source

Enhancing selenium biofortification: strategies for improving soil-to-plant transfer

Chemical and Biological Technologies in Agriculture
Selenium (Se) is one of the essential trace elements for humans. Plants are the main source of Se for humans, while soil Se is the primary source of Se for plants.
Qing Liao, Ying Xing, Ao-Mei Li, Pan-Xia Liang, Ze-Pu Jiang, Yong-Xian Liu, Dong-Liang Huang   +6 more
doaj   +1 more source

Značenja glagola smijati se, nasmijati se i nasmiješiti se

Jezik : časopis za kulturu hrvatskoga književnog jezika, 2021
Svrha je rada odrediti značenjske sličnosti i razlike triju glagola istoga korijena: smijati se, nasmijati se i nasmiješiti se. Nakon uvida u postojeće rječničke odrednice provest će se semantičko-sintaktička analiza spomenutih glagola s obzirom na pozitivne i negativne konotacije, i to uz načinske priloge, priloške oznake i poredbe (uključujući ...
openaire   +1 more source

Clinical trial of safety and antitumor activity of farletuzumab ecteribulin in patients with platinum‐resistant ovarian cancer: Phase I expansion results

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective In the dose‐escalation part of Study 101, which included multiple tumor types, objective responses were observed in 10 of 22 patients across multiple dose levels of farletuzumab ecteribulin (FZEC). We explored the safety/antitumor activity of FZEC in patients with platinum‐resistant ovarian cancer (PROC) from the Study 101 expansion ...
Kan Yonemori, Mayu Yunokawa, Koji Matsumoto, Kazuhiro Takehara, Kosei Hasegawa, Yasuyuki Hirashima, Hidenori Kato, Hiroki Ikezawa, Yohei Otake, Wataru Yusa, Takuma Miura, Shin Nishio   +11 more
wiley   +1 more source

Evaluation of Ceftriaxone as a Monotherapy and Amoxicillin With Clavulanic Acid as Combination Therapy in Surgical Prophylaxis

iNew Medicine, EarlyView.
ABSTRACT Surgical antibiotic prophylaxis (SAP) is crucial in preventing postoperative surgical site infections (SSIs), especially in clean and clean‐contaminated surgeries. It was a prospective comparative observational study that compared the effectiveness and safety of single‐dose ceftriaxone monotherapy with amoxicillin–clavulanic acid as a ...
Anayat Ullah, Arsh Ali, Md Nematullah, Suriya Kumar Singh, Anant Singh Paliwal, Najish Parveen   +5 more
wiley   +1 more source

SUMOylation regulates tumorigenesis and progression: Molecular mechanisms and therapeutic applications

Interdisciplinary Medicine, EarlyView.
SUMOylation, a dynamic post‐translational modification, acts as a master regulator at the heart of tumor malignancy. Our work delineates how the SUMOylation cycle—mediated by E1/E2/E3 enzymes and reversed by SENPs—orchestrates multiple hallmarks of cancer. The central pathway converges on three critical pathological axes: 1.
Yimao Wu, Zichang Chen, Yinting Hu, Gokhan Zengin, Qian Zhang, Meng‐Yao Li, Wenlong Sun   +6 more
wiley   +1 more source

A narrativa mediada e a permanência da tradição: percurso de um anti-herói brasileiro

Estudos de Literatura Brasileira Contemporânea, 2011
The article describes a narrative analysis of the song “Faroeste Caboclo”, written by the Brazilian composer Renato Russo. It freely applies the procedures proposed by the Russian narratologist Vladimir Propp in a typical product of the cultural industry
Luiz Gonzaga Motta
doaj  

Navigating ESG in the Artificial Intelligence Era: Evidence From AI Pilot Zones in China

International Studies of Economics, EarlyView.
ABSTRACT Artificial intelligence is reshaping business models, but limited literature explores how ESG evolves in the AI era. This paper regards AI Pilot Zones in China as a quasi‐natural experiment, and adopts the DID approach to investigate its impact on corporate ESG performance. Using the sample of Chinese A‐share listed companies from 2016 to 2022,
Yujie Liu, Xinyi Shen
wiley   +1 more source