Results 1 to 10 of about 19,506,624 (218)

EVT‐701 is a novel selective and safe mitochondrial complex 1 inhibitor with potent anti‐tumor activity in models of solid cancers

Pharmacology Research & Perspectives, 2021
Targeting the first protein complex of the mitochondrial electron transport chain (MC1) in cancer has become an attractive therapeutic approach in the recent years, given the metabolic vulnerabilities of cancer cells. The anticancer effect exerted by the
Raquel Luna Yolba, Virgile Visentin, Caroline Hervé, Johanna Chiche, Jean‐Ehrland Ricci, Jérôme Méneyrol, Michaël R. Paillasse, Nathalie Alet   +7 more
doaj   +1 more source

Transport study of interleukin-1 inhibitors using a human in vitro model of the blood-brain barrier

Brain, Behavior, & Immunity - Health, 2021
The proinflammatory cytokine Interleukin-1 (IL-1), with its two isoforms α and β, has important roles in multiple pathogenic processes in the central nervous system.
Elisabet O. Sjöström, Maxime Culot, Lisa Leickt, Mikael Åstrand, Erik Nordling, Fabien Gosselet, Christina Kaiser   +6 more
doaj   +1 more source

Air Transport System Agility: The Agile Response Capability (ARC) Methodology for Crisis Preparedness

Infrastructures, 2022
Aviation is a highly inter-connected system. This means that a problem in one area may cause effects in other countries or parts of the Air Transport System (ATS). Examples range from local air traffic disruptions to the 2010 volcanic ash crisis. Agility,
Rogier Woltjer, Björn J. E. Johansson, Per-Anders Oskarsson, Peter Svenmarck, Barry Kirwan   +4 more
doaj   +1 more source

Evaluation of Nearshore and Offshore Water Quality Assessment Using UAV Multispectral Imagery

Remote Sensing, 2020
A cost-effective technology has emerged which combines multispectral sensors mounted on Unmanned Aerial Vehicles (UAVs). This technology has a promising potential for monitoring water quality in coastal environments.
Ryan McEliece, Shawn Hinz, Jean-Marc Guarini, Jennifer Coston-Guarini   +3 more
doaj   +1 more source

Chromatic aberrations correction of attosecond high-order harmonic beams by flat-top spatial shaping of the fundamental beam

New Journal of Physics, 2023
Attosecond pulses created by high-order harmonic generation in gases often exhibit strong chromatic aberrations, arising from the broad bandwidth and wavelength-dependent nonlinear light–matter interaction.
K Veyrinas, M Plach, J Peschel, M Hoflund, F Catoire, C Valentin, P Smorenburg, H Dacasa, S Maclot, C Guo, H Wikmark, A Zaïr, V Strelkov, C Picot, C Arnold, P Eng-Johnsson, A L’Huillier, E Mével, E Constant   +18 more
doaj   +1 more source

From Cohort to Cohort: A Similar Mixture Approach (SMACH) to Evaluate Exposures to a Mixture Leading to Thyroid-Mediated Neurodevelopmental Effects Using NHANES Data

Toxics, 2023
Prenatal exposure to a mixture (MIX N) of eight endocrine-disrupting chemicals has been associated with language delay in children in a Swedish pregnancy cohort.
Maria Sapounidou, Patrik L. Andersson, Michelle Leemans, Jean-Baptiste Fini, Barbara Demeneix, Joëlle Rüegg, Carl-Gustaf Bornehag, Chris Gennings   +7 more
doaj   +1 more source

On the Needs and Requirements Arising from Connected and Automated Driving

Journal of Sensor and Actuator Networks, 2020
Future 5G systems have set a goal to support mission-critical Vehicle-to-Everything (V2X) communications and they contribute to an important step towards connected and automated driving.
Konstantinos Antonakoglou, Nadia Brahmi, Taimoor Abbas, Antonio Eduardo Fernandez Barciela, Mate Boban, Kai Cordes, Mikael Fallgren, Laurent Gallo, Apostolos Kousaridas, Zexian Li, Toktam Mahmoodi, Erik Ström, Wanlu Sun, Tommy Svensson, Guillaume Vivier, Jesus Alonso-Zarate   +15 more
doaj   +1 more source

Designing the Next Generation of Condition Tracking and Early Warning Systems for Shellfish Aquaculture

Journal of Marine Science and Engineering, 2021
Early detection of environmental disturbances affecting shellfish stock condition is highly desirable for aquaculture activities. In this article, a new biophysical model-based early warning system (EWS) is described, that assesses bivalve stock ...
Jean-Marc Guarini, Shawn Hinz, Jennifer Coston-Guarini   +2 more
doaj   +1 more source

Effects of the dopant concentration in laser wakefield and direct laser acceleration of electrons

New Journal of Physics, 2018
In this work, we experimentally study the effects of the nitrogen concentration in laser wakefield acceleration of electrons in a gas mixture of hydrogen and nitrogen.
I Gallardo González, H Ekerfelt, M Hansson, T L Audet, B Aurand, F G Desforges, S Dobosz Dufrénoy, A Persson, X Davoine, C-G Wahlström, B Cros, O Lundh   +11 more
doaj   +1 more source

Hydrocarbon Pollution Detection and Mapping Based on the Combination of Various Hyperspectral Imaging Processing Tools

Remote Sensing, 2021
Oil extraction and transportation may lead to small or large scale accidental spills, whether at sea or on land. Detecting these spills is a major problem that can be addressed by means of hyperspectral images and specific processing methods.
Véronique Achard, Pierre-Yves Foucher, Dominique Dubucq   +2 more
doaj   +1 more source